Novel Neuraminidase (NA) inhibitor

Novel Anti-Wolbachia Agent with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

DNA polymerase lambda and beta inhibitor

Novel inhibitor of the replication of a disease-causing polyomavirus in cell culture

Novel small molecule prodrug for use with SEAKER cells, exhibiting enhanced anticancer activity

Novel potent inhibitor of peroxiredoxin I (PrxI), increasing cellular ROS, leading to the activation of both mitochondria- and apoptosis signal-regulated kinase-1-mediated signaling pathways

Novel Metallo-β-lactamase Inhibitor

Novel agonist of AMPK signaling

Potent allosteric activator of the AMPK

Potent allosteric activator of AMPK

Novel rapid and specific inhibitor of electrophile-sensitive DEAD-box proteins with high selectivity over the wild-type enzyme

The most potent AMPA stabilizer

Potent A1/A2A adenosine receptor agonist, protecting against myocardial infarction

Light-activated DNA, RNA crosslinking agent

L-type calcium channel blocker

Inhibitor of the re-uptake of norepinephrine and serotonin, inhibiting N-methyl-D-aspartate (NMDA) receptors

Immunomodulator

NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor

Radiation-protective agent, causing splenic vasodilation and blocking autonomic ganglia

Cysteine trapping agent, protecting cysteines exposed to the aqueous environment from subsequently added mal-PEG

Specific transient receptor potential ankyrin 1 (TRPA1) antagonist

Novel vanilloid receptor TRPV1 modulator

Novel vanilloid receptor TRPV1 modulator

Vanilloid receptor TRPV1 antagonist

Novel highly specific phosphodiesterase 10A (PDE10A) ligand with good uptake in the striatum

Novel Disrupter of Glucokinase−Glucokinase Regulatory Protein (GK−GKRP) Binding

Novel potent and selective inhibitor of c-Kit

Novel potent DPP-IV inhibitor

Potent and selective TRPV1 antagonist

Novel selective IRE1α inhibitor