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Cat. No. Product Name Field of Application Chemical Structure
DC36635 1,10-Decanedicarboxylic acid
Dodecanedioic acid informally referred to as DDDA is a saturated aliphatic dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitor, surfactant, and plastics. Experimental work with Dodecanedioic acid in type 2 diabetic patients has demonstrated that IV infusion helps to maintain normal blood sugar and energy levels without increasing the blood glucose load in the process.
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DC36609 3-Deazaadenosine
3-Deazaadenosine is a potent inhibitor of adenosine deaminase, an enzyme that catalyzes the removal of the amine group from adenosine. This compound exhibits antitumor activity against a range of leukemia cell lines. 3-Deazaadenosine is an inhibitor of SAHH.
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DC36603 Deacylketoconazole
Deacylketoconazole is a Ketoconazole derivative. Ketoconazole is an antifungal medication which is used primarily to treat fungal infections.
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DC36597 Desacetylcefotaxime
Desacetylcefotaxime also known as 3-Desacetyl cefotaxime, is an impurity of cefotaxime sodium salt (sc-202989), a broad-spectrum cephalosporin antibiotic.
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DC36556 Dodecyl benzene sulfonic acid
Dodecyl benzene sulfonic acid, Dopant for conducting polymers strong acid catalyst for amino cross-linked coatings.
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DC36525 Thiamine disulfide
Thiamine is a essential nutrient required for carbohydrate metabolism; also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products, vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to Thiamine diphosphate, a coenzyme in the decarboxylation of α-keto acids. Chronic deficiency may lead to neurological impairment, bariberi, Wernicke-Korsakoff syndrome.
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DC36496 Bauerenol
Bauerenol is a triterpenoid from Indian Suregada angustifolia, is isolated from the stem bark of Acronychia pedunculata., Induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma (HepG2) cells. Bauerenol is an Antitrypanosomal Agent.
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DC36487 Cyclosporin B
Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts.
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DC36472 Bromosulfalein
Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2). It has also been used for in vivo studies of liver and biliary system function and as an anionic dye for the quantitative estimation of protein levels in tissue homogenates or purified samples.
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DC36464 Avermectin B1a monosaccharide
Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a.
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DC36458 NCI 240899
True Blue is a fluorescent neuronal retrograde tracer that labels the nucleus, nucleolus, cell body, proximal dendrites, and axons of neurons. It displays excitation/emission maxima of 373/404 nm, respectively.
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DC36449 Territrem B
Territrem B is a mycotoxin that irreversibly inhibits acetylcholinesterase (AChE). It is toxic to mice, inducing tremors with a median tremulous dose of 0.21 mg/kg.
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DC36448 Aburamycin A
Chromomycin A2 is an aureolic acid that has antibacterial and anticancer activities. Chromomycin A2 inhibits the growth of human SGC7901 gastric cancer, HepG2 hepatocellular carcinoma, A549 lung epithelial adenocarcinoma, HCT116 colon cancer, and COC1 ovarian cancer cells, as well as human umbilical vein endothelial cells (HUVECs). Chromomycin A2 halts the cell cycle in the G0/G1 phase and increases the protein levels of LC3A and LC3B in MALME-3M melanoma cells. This indicates that it induces autophagy. It also increases the levels and promoter activity of the autophagic proteins ATG7 and ATG10 and reduces cell viability to 50% in human SCC-11 squamous cell carcinoma cells when used at a concentration of 30 nM.
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DC36390 LysoFP-NH2
LysoFP-NH2 is the fluorescent form of the lysosomal turn-on fluorescent probe for carbon monoxide (CO) lysoFP-NO2. LysoFP-NH2 is formed when lysoFP-NO2 reacts with CO. It displays excitation/emission maxima of 440/528 nm, respectively.
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DC36365 Rugulotrosin A
Rugulotrosin A is an antibiotic active against the Gram-positive bacteria E. faecalis, B. cereus, B. subtilis, and S. aureus. Rugulotrosin A is inactive against Gram-negative bacteria.
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DC36351 (E)-Feruloyltyramine
Alfrutamide is a phenolic amide that has diverse biological activities including anti-inflammatory, antioxidative, and antiproliferative properties. It decreases nitric oxide (NO) production and inducible NO synthase (iNOS) activity and increases NO scavenging without inducing cytotoxicity. It also scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in TLC autographic and spectrophotometric assays.
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DC36337 Antibiotic XK-62-2 sulfate
Micronomicin sulfate is an aminoglycoside antibiotic originally isolated from Micromonospora. It is active against S. aureus, B. subtilis, B. cereus, E. coli, and K. pneumoniae.
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DC36315 N-Dipropyldopamine hydrobromide
N,N-Dipropyldopamine HBr is a dopamine receptor agonist. It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum as well as reduces homovanillic acid (HVA) levels. N,N-Dipropyldopamine reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.
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DC36314 Urapidil HCl
Urapidil HCl is an antagonist of α1-adrenergic receptors (α1-ARs) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. Urapidil HCl inhibits cAMP accumulation induced by forskolin. It is also a β1-AR antagonist that inhibits the positive chronotropic response induced by isoproterenol. Urapidil HCl lowers mean arterial pressure (MAP) in anesthetized cats, an effect that is reduced by central administration of the 5-HT1A receptor antagonist spiroxatrine.
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DC36295 Peonidin 3-O-glucoside
Peonidin 3-O-glucoside is a metabolite of cyanidin 3-glucoside and an anthocyanin with antioxidant, anti-inflammatory, antiproliferative, and anti-metastatic properties. Peonidin 3-O-glucoside inhibits IL-1β-induced phosphorylation of IKKα, IκBα, and ERK in human articular chondrocytes. Peonidin 3-O-glucoside inhibits the growth of Hs578T human breast cancer cells in vitro in a concentration-dependent manner and decreases pulmonary metastasis in a mouse model of Lewis lung carcinoma.
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DC36283 3-Hydroxyterphenyllin
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite with antioxidant, antiproliferative, antibacterial, and antiviral properties. 2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria. It also inhibits HIV-1 integrase in both coupled and strand transfer assays.
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DC36246 4-oxo Withaferin A
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.
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DC36230 3H-Amt
Aminomethyltrioxsalen is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.
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DC36220 AI3-51572
ATMP, or aminotris(methylenephosphonic acid), is a phosphonic acid with chelating properties. It is an antiscalant.
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DC36212 (R)-Amisulpride
Amisulpride, (R)-, is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
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DC36166 AI3-31843
Rhododendrol, (+/-)-, is an aromatic compound that may be useful in the treatment of hepatic diseases. However, this product is a known pro-oxidant which can be toxic to melanocytes.
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DC36139 AY 21554
Talopram hydrochloride is a the HCl salt of Talopram -- a selective norepinephrine reuptake inhibitor (NRI). Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram, as well as to melitracen.
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DC36130 Ankerbin
Cloxacillin Sodium is a semi-synthetic antibiotic that is a chlorinated derivative of Oxacillin. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase.
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DC36127 AI3-29785
Chlorfluazuron is a chitin synthesis inhibitor. Chlorfluazuron is commonly used in agriculture as an insect growth regulator for controlling the major insect pests in crops
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DC36118 Ageratochromene
Precocene II is an antiallotropin compound capable of inhibiting juvenile hormone biosynthesis. Precocene II has antibacterial, antifungal, insecticidal, and antioxidant activities.
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