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Cat. No. Product Name Field of Application Chemical Structure
DC36890 Kirromycin
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis.
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DC36887 Pachycarpine
Pachycarpine may decrease hyperexcitability through the activation of the M2 and M4 subtypes of mAChRs, which is a probable mechanism of action that together with its systemic effects may favor its anticonvulsant effects against seizures and SE.
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DC36885 VU 0650991
VU 0650991 is a non-competitive GLP-1 antagonist that is orally bioavailable and acts as a brain penetrant.
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DC36871 Neocuproine
Neocuproine is a copper(I) chelator.
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DC36863 Mitraphylline
Mitraphylline is isolated from Uncaria tomentosa and has potential anti-inflammatory activity.
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DC36862 Totarol
Totarol is a diterpene originally isolated from P. totara that has diverse biological activities, including antibacterial, antioxidant, and neuroprotective properties.
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DC36850 m 15
m 15 liquid crystals are a member of the oxycyanobiphenyl family. They exhibit liquid crystalline phase in the temperature range of 47-67.5oC. H NMR of the phase transitions has been studied.
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DC36836 Hexazinone
Hexazinone is an organic compound that is used as a broad spectrum herbicide.
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DC36831 Piperitenone
Piperitenone is a monoterpene that has been found in various plants, has antioxidant activity and inhibits peroxidation of linoleic acid
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DC36827 Lynestrenol
Lynestrenol is a synthetic progestational hormone used often in mixtures with estrogens as an oral contraceptive.
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DC36821 KT 1
KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs.
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DC36806 Ginkgetin
Ginkgetin is a biflavonoid that has been isolated from G. biloba and has diverse biological activities, including pro-apoptotic, antiproliferative, anti-inflammatory, anti-atherosclerosis, and neuroprotective properties.
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DC36774 Paramethasone
Paramethasone is a glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than Hydrocortisone with supplementary Fludrocortisone.
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DC36769 Phenobarbital
Phenobarbital is a barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations. Phenobarbital is discontinued.
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DC36734 Cystamine
Cystamine, also known as Aminoethyl-SS-ethylamine, is a cleavable PEG Linker and radiation-protective agent that interferes with sulfhydryl enzymes. It may also protect against carbon tetrachloride liver damage.
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DC36706 Deceth-6
Deceth-6 is a nonionic surfactant useful for proteomics research.
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DC36672 Rorifone
Rorifone is a biochemical.
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DC36644 Decan-5-ol
Decan-5-ol is a biochemical.
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DC36631 Decalin-1,4-dione
Decalin-1,4-dione is a biochemical.
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DC36565 DDT
DDT is a polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen.
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DC36503 Calcium carbonate
Calcium carbonate is a naturally occurring compound used as a calcium supplement and antacid. Also used in laboratories as a buffer. Shown in renal-disease patients with hyperphosphatemia to contain phosphate binding power, but may result in hypercalcaemia or alkalosis. Other experiments have successfully utilized calcium carbonate as a calcium control in comparison studies.
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DC36495 Carboxin
Carboxin is a systemic agricultural fungicide and seed treatment agent. Carboxin kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.
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DC36419 Iloperidone metabolite P95
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors but does not cross the blood-brain barrier.
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DC36413 Aspergillin PZ
Aspergillin PZ is a fungal metabolite active against S. epidermidis but not S. aureus, E. coli, or B. cereus. It is cytotoxic to HL-60 promyelocytic leukemia cells but not THP-1 acute monocytic leukemia or PC3 prostate cancer cells.
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DC36398 9-Methylstreptimidone
Antibiotic TS 885 is a microbial metabolite that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro. 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
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DC36324 Chlamydocin
Chlamydocin is a histone deacetylase (HDAC) inhibitor with anticancer properties. Chlamydocin increases acetylation of histone H3 and histone H4 and inhibits growth of A2780, Malme-3M, MCF-7, HT-29, and HeLa cancer cells. Chlamydocin also increases lifespan by 10% in a P185 mouse allograft model.
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DC36296 NSC 5897
Vulpinic acid is a lichen metabolite with diverse biological activities. It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus. Vulpinic acid prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes. It also increases scratch wound healing of HaCaT cells. Vulpinic acid reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cytotoxicity in human umbilical vein endothelial cells (HUVECs).
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DC36292 Dihydrokainic acid
Dihydrokainic acid is an inhibitor of excitatory amino acid transporter 2 (EAAT2). EEAT2 exhibits anti-depressant-like activity --- an effect that is blocked by the AMPA receptor antagonist NBQX and the serotonin (5-HT) receptor subtype 5-HT1A antagonist WAY-100635. It also increases glutamate and serotonin levels and the expression of c-Fos in the dorsal raphe nucleus. It also impairs memory acquisition, consolidation, and retrieval.
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DC36248 (+)-Pinoresinol
(+)-Pinoresinol is a lignan that diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase. (+)-Pinoresinol scavenges ABTS but not 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in cell-free assays. It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37 cells. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells and inhibits LPS-induced nitric oxide production in RAW 264.7 cells.
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DC36218 Aminacrine hydrochloride monohydrate
Aminacrine hydrochloride monohydrate is a highly fluorescent anti-infective dye used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.
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