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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC35038 Benzyl-PEG2-Tos
Benzyl-PEG2-Tos is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34945 Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine
Boc-Gly-amido-(CH2)3-PEG3-(CH2)3-amine is an Amino PEG Linker. PEG Amines contain an amino group which can react with acids, succinimidyl-active esters, or pentafluorophenyl esters for labeling, chemical modification, surface or particle modifications. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34921 Azido-PEG5-amine
Azido-PEG5-amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34916 Amino-PEG11-amine
Amino-PEG11-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates or drug delivery methods.
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DC34914 Amino-PEG9-amine
Amino-PEG9-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34843 Propargyl-PEG2-acrylate
Propargyl-PEG2-acrylate is a PEG derivative containing a propargyl group and an acrylate group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The acrylate group enables Michael addition. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery.
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DC34785 Propargyl-PEG1-t-butyl ester
Propargyl-PEG1-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34769 2-Iminothiolane
2-Iminothiolane HCl, or Traut's Reagent,is commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation. It is a useful RNA-protein crosslinking reagent and an effective thiolation reagent for polysaccharides.
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DC34754 CDI Crosslinker
CDI Crosslinker, or N,N'-Carbonyldiimidazole, is a zero-length crosslinker that is often employed in the coupling of amino acids for peptide synthesis and also in organic synthesis. CDI can be used to convert alcohols and amines into carbamates, esters, and ureas.
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DC34715 Achillein
Betonicine can be found in herbs and spices and pulses, which makes betonicine a potential biomarker for the consumption of these food products. Betonicine can be found primarily in urine. This compound belongs to the class of organic compounds known as l-alpha-amino acids.
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DC34693 Abminthic
Dithiazanine iodide is a benzothiazole that has been used as an antinematodal agent. Also, it has been effective as a nanoparticle in treating glioblastoma.
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DC34691 Abietic acid
Abietic acid has been investgated as an antimetastatic agent or as an adjuvant for anticancer therapy.
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DC34671 Blastomycin
Blastomycin, also known as Antimycin A3, is an antigen for intradermal testing prepared from sterile filtrates of cultures of the filamentous form of Blastomyces dermatitidis. It acts as a fungicide, bactericide, and wood preservative.
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DC34580 Manumycin A
Manumycin A is a Farnesyltransferase inhibitor which suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells, inhibiting IKKβ activity through covalent cross-linking of IKKβ monomers via C179.
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DC34566 Galnon
Galnon is a selective, non-peptide agonist at the galanin receptors GALR.
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DC34539 Echimidine
Echimidine is one of the natural predominant pyrrolizidine alkaloids (PAs) found in honeys produced in Australia and New Zealand. Echimidine activates PXR and induces PXR-mediated CYP3A4 expression.
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DC34536 OKG
Ornithine-α-ketoglutarate is a modulator of the respiratory burst via nitric oxide and polyamine generation, thereby improving immune status during stress.
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DC34517 Chalinasterol
24-Methylenecholesterol is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.
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DC34485 Delphinidin Chloride
Delphinidin Chloride is an inhibitor of BDNF-induced migration and invasion in SKOV3 ovarian cancer cells.
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DC34483 ATC0065 dihydrochloride
ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist.
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DC34480 Cerebrosterol
Cerebrosterol is a major brain metabolite of cholesterol.
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DC34429 L-NMMA acetate
L-NMMA acetate is an endothelium-derived relaxing factor inhibitor. It acts by inhibiting the generation of NO from arginine.
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DC34428 A1899
A1899 is a potent and selective TASK-1 and TASK-3 antagonist.
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DC34409 8-Br-cGMP
8-Br-cGMP is an activator of cGMP-dependent protein kinase. It acts by inhibiting the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine.
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DC34396 (R)-Pantetheine
(R)-Pantetheine is a metabolite in carbapenem biosynthesis, pantothenate and CoA biosynthesis and biosynthesis of secondary metabolites.
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DC34375 PMX464
PMX464 is a cytocidal anti-trypanosomal inhibitor that acts by targeting trypanothione metabolism. It is also a putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system.
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DC34370 MMPIP Hydrochloride
MMPIP HCl is an allosteric mGlu7-selective receptor antagonist.
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DC34362 Ononetin
Ononetin is a TRPM3 channel blocker.
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DC34308 MS438
MS438 is a potent agonist of the TSH receptor (TSHR).
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DC34290 BAMF
BAMF is an acetylating agent for the chemical modification of proteins.
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