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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC34906 Amino-PEG1-amine
Amino-PEG1-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34893 Amino-PEG3-t-butyl ester
Amino-PEG3-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34770 HPG Protein Modifier
HPG Protein Modifier, or p-Hydroxyphenylglyoxal, reacts with arginine residues to give a large increase in absorbance at approximately 340 nm, and hence, is a good choice for amino acid side chain modification.
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DC34756 EDC-HCl Crosslinker
EDC-HCl Crosslinker is a zero-length crosslinker that can be used to conjugate carboxyl functional groups to primary amines. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals.
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DC34726 NSC 3910
Quinoclamine induces cell differentiation in HL-60 cells.
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DC34701 Benzoximate
Benzoximate is an insecticide and acaricide.
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DC34688 Oxametacin
Oxametacin is a anti-inflammatory compound used with care in anticoagulated patients. It has analgesic, antipyretic and anti-inflammatory properties comparable to those of indomethacin.
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DC34655 Triethoxycaprylylsilane
Triethoxycaprylylsilane is an organically modified silane that has been found to aggregate in the form of normal micelles as well as reverse micelles. The molecule can be hydrolyzed to form a hydrated silica network while the n-octyl groups are held together through hydrophobic interaction. The network can host hydrophobic molecules through interactions with the hydrophobic core and the hydrophilic silica cores can encapsulate hydrophilic molecules such as horseradish peroxidase (HRP). Triethoxycaprylylsilane is commonly used in plastics applications.
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DC34639 Disperse Orange 1
DO1, also known as Disperse Orange 1, is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations, thereby disrupting preformed fibrillar assemblies of synthetic Aβ42 peptides.
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DC34629 Flumethasone 21-acetate
Flumethasone 21-acetate is an anti-inflammatory corticosteroid.
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DC34627 BV 02
BV02 is an inhibitor of SFN. It also targets YWHAZ of the 14-3-3 protein family.
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DC34612 Thyroid Hormone Receptor Antagonist (1-850)
TR-IN-1-850 is a selective blocker of T3 binding to both TRα and TRβ.
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DC34597 Naphthol AS-TR phosphate
NASTRp is an inhibitor of CREB-CBP complex which possesses anti-cancer effects along with cell cycle regulation, autophagy suppression, and endoplasmic reticulum stress.
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DC34544 Loline
Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oat aphid (genus Rhopalosiphum), large milkweed bug (Oncopeltus fasciatus), and American cockroach (Periplaneta americana), thereby protecting the host plant from insect herbivory.
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DC34542 Asperulosidic Acid
Asperulosidic Acid is a natural glycoside which inhibits both AP-1 transactivation, and cell transformation, in the mouse epidermal JB6 cell line.
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DC34494 Shaoguanmycin B
Piericidin A is an irreversible inhibitor of mitochondrial complex I that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of the enzyme. Piericidin A induces transcription of the p53-responsive SESN2 gene which plays an important role in the stress response and homeostatic regulation.
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DC34475 AalphaC
AalphaC is a potential human carcinogen.
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DC34419 NAEPA
NAEPA is a selective lysophosphatidic acid-1 (LPA1) receptor agonist and a LPA mimetic.
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DC34403 MSX-2
MSX-2 is a selective A2A adenosine receptor antagonist.
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DC34374 N12N
N12N is a polyamine inverse agonist of NMDA receptor.
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DC34369 GRK2 Inhibitor
GRK2 Inhibitor is an inhibitor of GRK 2 (β-Adrenergic Receptor Kinase 1).
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DC34364 MRE 3008-F20
MRE 3008-F20 is a potent antagonist of the human A3 adenosine receptors.
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DC34276 TRIM
TRIM is an nNOS inhibitor.
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DC34263 Tyrphostin 1
Tyrphostin 1 is an EGFR tyrosine kinase inhibitor.
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DC34229 Monoelaidin
Monoelaidin is an enhancer of the solubility and oral bioavailability for poorly water-soluble drugs.
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DC34207 J-104129 fumarate
J-104129 fumarate is a potent M3 muscarinic receptor antagonist.
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DC34189 CYMAL-5
CYMAL-5 is an additive for gel-based membrane proteomics.
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DC34188 Robenidine hydrochloride
Robenidine hydrochloride is an antibiotic used for the control of coccidiosis, a debilitating protozoal infection in poultry.
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DC34186 Thioflavin T
Thioflavin T is a widely used dye for visualizing and quantifying the presence of misfolded protein aggregates called amyloid, both in vitro and in vivo.
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DC34184 DAPI Dihydrochloride
DAPI Dihydrochloride is a cell-permeable fluorescent probe used to stain DNA and chromosomes, with a preference for adenine and thymine rich DNA.
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