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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC36243 CAY10735
CAY10735 is an anticancer compound that inhibits proliferation of melanoma, breast, pancreatic, and lung cancer cell lines by inhibiting the epithelial-to-mesenchymal transition (EMT).
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DC36191 AM-3102
AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.
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DC36182 Altimol
Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase. This enzyme crucial to the metabolism of alcohol and is suitable for aldehyde dehydrogenase (ALDH) related research.
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DC36164 AI3-52581
Canavanine sulfate is a biochemical with antimutagenic activity. This product has been shown to potentiate the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells
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DC36159 AI3-51270
Methylguanidine hydrochloride is a biochemical that can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.
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DC36158 3177 R.P.
Melarsen oxide is a glutathione reductase inhibitor.
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DC36057 Pyrantel pamoate
Pyrantel pamoate is a broad spectrum antinematodal anthelmintic.
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DC36054 N-Antipyrinylnicotinamide
Nifenazone is a drug used as an analgesic for a number of rheumatic conditions.
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DC36029 (2-pyridyldithio)-PEG2-t-butyl ester
(2-pyridyldithio)-PEG2-t-butyl ester is a thiol PEG Linker.
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DC36028 (2-pyridyldithio)-PEG4-propargyl
(2-pyridyldithio)-PEG4-propargyl is a PEG Linker.
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DC36014 S-acetyl-PEG4-alcohol
S-acetyl-PEG4-alcohol is a PEG Linker.
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DC35991 Methyltetrazine-PEG8-NHS ester
Methyltetrazine-PEG8-NHS ester is a PEG Linker.
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DC35984 Methyltetrazine-PEG8-acid
Methyltetrazine-PEG8-acid is a PEG Linker
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DC35977 TCO-PEG4-biotin
TCO-PEG4-biotin is a PEG Linker containing a TCO moeity.
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DC35937 Tos-PEG4-t-butyl ester
Tos-PEG4-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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DC35866 N-Mal-N-bis(PEG4-NH-Boc)
N-Mal-N-bis(PEG4-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.
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DC35865 N-Mal-N-bis(PEG2-NH-Boc)
N-Mal-N-bis(PEG2-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.
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DC35862 N-Mal-N-bis(PEG2-NHS ester)
N-Mal-N-bis(PEG2-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35859 N-Mal-N-bis(PEG4-amine) TFA
N-Mal-N-bis(PEG4-amine) TFA salt is a branched PEG derivative with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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DC35858 N-Mal-N-bis(PEG2-amine) TFA
N-Mal-N-bis(PEG2-amine) TFA salt is a branched PEG derivative with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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DC35832 Mal-amido-PEG9-amine TFA
Mal-amido-PEG9-amine TFA salt is a PEG derivative containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35824 Mal-amido-PEG9-NHBoc
Mal-amido-PEG9-NHBoc is a PEG derivative containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected by acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35786 N-(t-butyl ester-PEG3)-N-bis(PEG3-azide)
N-(t-butyl ester-PEG3)-N-bis(PEG3-azide) is a branched PEG derivative with two terminal azide group and a t-butyl ester. The azide groups enable PEGylation via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under mild acidic conditions.
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DC35777 N-(NHS-PEG3)-N-bis(PEG3-azide)
N-(NHS-PEG3)-N-bis(PEG3-azide) is a branched PEG derivative with two terminal azide groups and a terminal NHS ester. The azide groups enable PEGylation via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35776 N-(Azido-PEG4)-N-bis(PEG4-NHS ester)
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a branched PEG derivative with a terminal azide group and two terminal NHS esters. The azide group enables PEGylation via Click Chemistry. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35768 N-(acid-PEG3)-N-bis(PEG3-azide)
N-(acid-PEG3)-N-bis(PEG3-azide) is a branched PEG derivative with two terminal azide groups and a terminal carbozylic acid. The azide groups enables PEGylation via Click Chemistry. The terminal carboxylic acid can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35764 N-(Azido-PEG3)-NH-PEG3-acid HCl
N-(Azido-PEG3)-NH-PEG3-acid HCl salt is a branched PEG derivative with a terminal azide group and terminal caboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, and carbonyls. The azide group enables PEGylation via Click Chemistry. The terminal carboxylic acid can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35741 APN-C3-PEG4-azide
APN-C3-PEG4-azide is part of a new class of thiol-specific conjugation reagents consisting of a thiol-reactive 3-arylpropiolonitrile (APN) group. This molecule has good stability in aqueous media. The APN group allows the targeted coupling of thiols in biomolecules, and results in stable thioether linkages without the risk of subsequent side reactions that can occur with maleimides.
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DC35738 Azide-PEG5-Tos
Azide-PEG5-Tos is a PEG derivative containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
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DC35735 Azido-PEG4-hydrazide HCl
Azido-PEG4-hydrazide HCl Salt is a PEG Linker.
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