Fenpyroximate is an acaricide and insecticide, blocking the mitochondrial electron transport in complex I.

rac-CCT-250863 is a potent Nek2 inhibitor. exhibiting selectivity for Nek2 over PLK1, MPS1, Cdk2 and Aurora A.

HHQ is an antagonist of PqsR.

Sulfaclozine is an antiprotozoal.

Piromidic acid is antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.

Physostigmine salicylate is a reversible cholinesterase inhibitor, a parasympathomimetic alkaloid. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

PDP-EA is an FAAH activator, enhancing amidohydrolase activity of FAAH.

Levoglucosenone is a cytotoxic, against human hepatocarcinoma cell lines.

PBI-51 is a competitive Inhibitor of Abscisic Acid-Regulated Gene Expression.

Propachlor is a specific ALDH1A1 inhibitor. It is sometimes used as an herbicide.

L-670596 is a potent and selective thromboxane A2/prostaglandin endoperoxide receptor antagonist, also showing ALDH1A1 specific inhibitory activity.

Rauwolscine hydrochloride is an alpha2-Adrenergic antagonist and partial agonist at 5-HT1A receptors.

Sulfidefluor-7 AM is a novel hydrogen sulphide (H2S) fluorescent probe.

Fenirofibrate is a metabolite of Fenofibrate.

LP117 is a novel drug-specific modulator of ABCB1-mediated drug transport.

Periciazine is a drug that belongs to the phenothiazine class of typical antipsychotics. Periciazine is used to treat short-term severe anxiety or tension and in the maintenance treatment of psychotic disorders such as schizophrenia.

Pencycuron, also known as Monceren, is a phenylurea fungicide.

PD-198306 is a cell-permeable amino-benzamide compound that acts as a potent and non-ATP-competitive inhibitor of MEK1/2 (IC50 = 8 nM) with an excellent selectivity over ERK, c-Src, Cdk's, and PI 3-Kγ (IC50 >1.0 μM).

NCL00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor.

PD-176252 is a non-peptide gastrin-releasing peptide receptor (GRP-R, BB2) and neuromedin B receptor (NMB-R, BB1) antagonist (Ki values are 0.17 and 1.0 nM for BB1 and BB2 respectively). It inhibits proliferation of rat C6 glioma cells (IC50 = 2 μM) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC50 = 5 μM).

TrxR-IN-D9, also known as D9, is a novel inhibitor of thioredoxin reductase (TrxR).

Tiaprost is a prostaglandin F2 alpha analogue as an estrus-synchronizing agent.

NB-64 is a novel human immunodeficiency virus type 1 (HIV-1) entry inhibitor, interferring with the gp41 six-helix bundle formation and blocking virus fusion.

Nitrocefin is an antibiotic, being sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria.

Oxantel is a fumarate reductase inhibitor; Anthelmintic.

(S)-alpha-Fluoromethylhistidine HCl is a potent irreversible histidine decarboxylase (HDC) inhibitor and glutathione S-transferase inhibitor. a-FMH was demonstrated to be an effective inhibitor of GST at micromolar concentration, suggesting that off-target effects of a-FMH may limit physiological drug metabolism and elimination by GST-dependent mechanisms.

PD 135158 is a Selective cholecystokinin type B (CCKB)/gastrin receptor agonist. In studies, PD- 135158 stimulates lipase release from isolated rat pancreatic acini dose dependently in a biphasic manner, with identical efficacy but lower potency compared to cholecystokinin octapeptide (CCK-8). PD 135158 is classified into Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, Psychotropic Drugs, and Tranquilizing Agents.

PD 109488 is a metabolite of quinapril. PD 109488, otherwise known as Quinapril Diketopiperazine, is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.

Papaverine Hydrochloride, USP, is the hydrochloride of an alkaloid obtained from opium or prepared synthetically. It belongs to the benzylisoquinoline group of alkaloids. It does not contain a phenanthrene group as do morphine and codeine. The most characteristic effect of papaverine is relaxation of the tonus of all smooth muscle, especially when it has been spasmodically contracted. Papaverine Hydrochloride apparently acts directly on the muscle itself. This relaxation is noted in the vascular system and bronchial musculature and in the gastrointestinal, biliary and urinary tracts.

Oxfenicine, also known as UK-25842, is a carnitine palmitoyltransferase I (CPT-1) inhibitor involved in fatty acid metabolism in the heart. In animal studies oxfenicine acts as a cardioprotective agent during ischemia. Oxfenicine produces changes in myocardial substrate utilisation and is attributed to the protection of ischemic stressed myocardium by shifting the cardiac metabolism with reduction of FFA (Free Fatty Acid) utilisation. This may be favourable in circumstances with limited oxygen supply.