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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC35476 | THP-PEG8-Tos |
THP-PEG8-Tos is a PEG linker. The PEG linker contains 7 units of ethylene glycol.
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| DC35474 | THP-PEG9 |
THP-PEG9 is a PEG Linker.
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| DC35418 | Hydroxy-PEG1-t-butyl ester |
Hydroxy-PEG1-t-butyl ester is a PEG derivative containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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| DC35416 | Hydroxy-PEG4-CH2CO2H |
Hydroxy-PEG4-CH2CO2H, sodium salt, is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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| DC35394 | Fmoc-NH-PEG11-CH2COOH |
Fmoc-NH-PEG11-CH2COOH is a PEG derivative containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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| DC35274 | Bis-Tos-(2-hydroxyethyl disulfide) |
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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| DC35223 | Bromo-PEG5-bromide |
Bromo-PEG5-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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| DC35164 | t-Boc-N-Amido-PEG3-azide |
t-Boc-N-Amido-PEG3-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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| DC35137 | Bis-PEG2-NHS ester |
Bis-PEG2-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).
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| DC35136 | Bis-PEG1-NHS ester |
Bis-PEG1-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates.
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| DC35056 | Biotin-PEG4-amine |
Biotin-PEG4-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Therefore, PEG Linkers can be useful in the development of antibody drug conjugates and drug delivery methods.
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| DC34909 | Amino-PEG4-amine |
Amino-PEG4-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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| DC34767 | Biotin Hydrazide |
Biotin Hydrazide, or Biotin-Hz, is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens.
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| DC34761 | NHS-LC-Biotin |
NHS-LC-Biotin, or Succinimidyl 6-(biotinamido)hexanoate, is an amino-reactive biotinylation reagent with a long spacer arm which helps alleviate steric hindrance. NHS-LC-Biotin is used to biotinylate proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains.
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| DC34752 | EGS Crosslinker |
EGS Crosslinker, or Ethylene glycol bis(succinimidylsuccinate), is a water insoluble homobifunctional crosslinker that can be used to label intracellular proteins. EGS crosslinker is often used in ChIP assays to determine DNA-protein binding interactions.
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| DC34748 | DSS Crosslinker |
DSS crosslinker, or Disuccinimidyl suberate, is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.
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| DC34717 | Ratic |
Ranitidine is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome.
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| DC34696 | Hydramethylnon |
Hydramethylnon is an insecticide primarily used for fire ants. It is poorly absorbed in the mammal body and leaves mostly unchanged.
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| DC34677 | Esfenvalerate |
Esfenvalerate is a common insecticide.
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| DC34662 | Chromonar hydrochloride |
Chromonar hydrochloride is a coronary vasodilator agent. It increases in transmural blood flow.
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| DC34650 | NCGC00063279 |
NCGC00063279 is a novel inhibitor of the werner syndrome helicase-nuclease (wrn) helicase
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| DC34640 | 6PNG |
6-PNG is a Cav3.2 (T-type) calcium channel blocker.
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| DC34637 | Rifamycin |
Rifamycin is a natural antibiotic which inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, thereby blocking RNA-polymerase transcription initiation.
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| DC34528 | Micheliolide |
Micheliolide is a natural, irreversible activator of pyruvate kinase M2, and a suppressor of leukemia cells.
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| DC34516 | TD3 |
TD-3 is an inhibitor of the salt-bridge formation between β-Asp94 and β-His146 hemoglobin (Hb), binding to Hb β-Cys93.
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| DC34491 | Halofuginone HBr |
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
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| DC34479 | NSC-57969 |
NSC-57969 is a MDR-selective agent, exhibiting a robust Pgp-dependent toxic activity across diverse cancer cell lines.
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| DC34469 | Enbucrilate |
Enbucrilate is a tissue adhesive, forming polymer films at oil-water interfaces and revealing films of diverse morphology.
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| DC34466 | Toltrazuril |
Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals.
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| DC34451 | HDAC8-IN-2 |
HDAC8-IN-2 is a selective HDAC8 inhibitor.
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