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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC35441 | PEG10-Tos |
PEG10-Tos is a PEG derivative containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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| DC35122 | Bis-PEG1-acid |
Bis-PEG1-acid is a PEG derivative containing two terminal carboxylic acid groups. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.
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| DC35061 | Biotin-PEG23-amine |
Biotin-PEG23-amine is PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Therefore, Biotin-PEG-amines may be useful in the development of antibody drug conjugates (ADCs).
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| DC35045 | Biotin-PEG2-NHS ester |
Biotin-PEG2-NHS ester is PEG derivative containing a biotin group and an NHS ester group. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds. PEG Linkers may be useful in the development of antibody drug conjugates.
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| DC35018 | Benzyl-PEG2-alcohol |
Benzyl-PEG2-alcohol is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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| DC34902 | Amino-PEG3-alcohol |
Amino-PEG3-alcohol is a PEG derivative containing an amino group with a hydroxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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| DC34894 | Amino-PEG4-t-butyl ester |
Amino-PEG4-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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| DC34750 | DST Crosslinker |
DST Crosslinker, or Disuccinimidyl tartrate, is a homobifunctional, cleavable crosslinking reagent (cleavable by oxidizing reagents). DST crosslinker is an excellent choice for applications in which crosslink cleavability is desired without disturbing protein disulfide bonds with reducing reagents.
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| DC34733 | MBS Crosslinker |
MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysuccinimide ester) is a non-cleavable, water insoluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The MBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively. Sulfo-MBS crosslinker is the water soluble analog of MBS protein crosslinker and is a convenient choice if you do not wish to use organic solvents to solubilize MBS protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog is SMPB crosslinker
SATA Protein Modifier can be used to add sulfhydryl groups (thiols, -SH) to proteins or peptides prior to MBS crosslinking.
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| DC34730 | ANB-NOS Crosslinker |
ANB-NOS Crosslinker, also known as N-5-Azido-2-nitrobenzoyloxysuccinimide, is a heterobifunctional protein crosslinker with a spacer arm length of 7.7 angstroms. The ANB-NOS crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups. ANB-NOS Crosslinker is useful for making ADCs (antibody drug conjugates).
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| DC34714 | Mericycline |
Tetracycline, sold under the brand name Sumycin among others, is an antibiotic used to treat a number of infections. This includes acne, cholera, brucellosis, plague, malaria, and syphilis. It possesses some level of bacteriostatic activity against almost all medically relevant aerobic and anaerobic bacterial genera, both Gram-positive and Gram-negative.
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| DC34713 | Ovisot |
Acetylcholine chloride is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
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| DC34703 | Acetylcysteine |
Acetylcysteine has been used to control irritability and aggressive behaviors in patients with autism and other neuropsychiatric disorders. Acetylcysteine has also been used in the treatment of patients with chronic bronchitis and chronic obstructive pulmonary disease (COPD).
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| DC34654 | Mephenesin |
Mephenesin is a centrally acting muscle relaxant with a short duration of action. It can be used as an antidote in strychnine poisoning.
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| DC34569 | Carboprost tromethamine |
Carboprost tromethamine is a Prostaglandin F2α analog.
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| DC34468 | BLI-489 Hydrate |
BLI-489 Hydrate is a novel beta-lactamase inhibitor.
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| DC34462 | PF-5274857 HCl |
PF-5274857 HCl is a potent and selective smoothened (Smo) receptor antagonist.
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| DC34457 | Nalmefene Hydrochloride |
Nalmefene HCl is an antagonist of the opioid receptors.
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| DC34432 | Brilliant Blue G |
Brilliant Blue G is a P2X7 purinergic receptor antagonist.
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| DC34383 | IDO1-IN-1 |
IDO1-IN-1 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1).
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| DC34322 | NBI-35965 Mesylate |
NBI-35965 Mesylate is a potent and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist.
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| DC34320 | Piperlonguminine |
Piperlonguminine is an inhibitor of Akt/mTOR signalling. It acts by promoting autophagy and mediating cancer cell death.
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| DC34309 | CJB-090 2HCl |
CJB-090 2HCl is a dopamine D3 receptor partial agonist.
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| DC34295 | Wee1 Inhibitor I |
Wee1 Inhibitor I is an ATP-binding site-targeting inhibitor of Wee1.
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| DC34281 | 6-OHDA HBr |
6-OHDA HBr is a neurotoxin. It acts by destroying catecholaminergic terminals.
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| DC34266 | Flu-IA |
Flu-IA is a fluorescent probe that covalently labels DNA fragments.
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| DC34260 | Methylarbutin |
Methylarbutin is an ice recrystallization inhibitor (IRI).
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| DC34213 | Amethopterin |
Amethopterin is a chemotherapy agent and immune system suppressant. It can treat cancer of the blood, bone, lung, breast, head, and neck. It can also treat rheumatoid arthritis and psoriasis.
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| DC34199 | CBBR |
CBBR is an inhibitor of wild type and mutant alpha-synuclein aggregation and a modulator of neurotoxicity. It is also used as a protein staining dye.
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| DC34178 | CBIO |
CBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception.
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