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Cat. No. Product Name Field of Application Chemical Structure
DC36631 Decalin-1,4-dione
Decalin-1,4-dione is a biochemical.
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DC36565 DDT
DDT is a polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen.
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DC36503 Calcium carbonate
Calcium carbonate is a naturally occurring compound used as a calcium supplement and antacid. Also used in laboratories as a buffer. Shown in renal-disease patients with hyperphosphatemia to contain phosphate binding power, but may result in hypercalcaemia or alkalosis. Other experiments have successfully utilized calcium carbonate as a calcium control in comparison studies.
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DC36495 Carboxin
Carboxin is a systemic agricultural fungicide and seed treatment agent. Carboxin kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.
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DC36419 Iloperidone metabolite P95
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors but does not cross the blood-brain barrier.
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DC36413 Aspergillin PZ
Aspergillin PZ is a fungal metabolite active against S. epidermidis but not S. aureus, E. coli, or B. cereus. It is cytotoxic to HL-60 promyelocytic leukemia cells but not THP-1 acute monocytic leukemia or PC3 prostate cancer cells.
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DC36398 9-Methylstreptimidone
Antibiotic TS 885 is a microbial metabolite that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro. 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
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DC36324 Chlamydocin
Chlamydocin is a histone deacetylase (HDAC) inhibitor with anticancer properties. Chlamydocin increases acetylation of histone H3 and histone H4 and inhibits growth of A2780, Malme-3M, MCF-7, HT-29, and HeLa cancer cells. Chlamydocin also increases lifespan by 10% in a P185 mouse allograft model.
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DC36296 NSC 5897
Vulpinic acid is a lichen metabolite with diverse biological activities. It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus. Vulpinic acid prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes. It also increases scratch wound healing of HaCaT cells. Vulpinic acid reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cytotoxicity in human umbilical vein endothelial cells (HUVECs).
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DC36292 Dihydrokainic acid
Dihydrokainic acid is an inhibitor of excitatory amino acid transporter 2 (EAAT2). EEAT2 exhibits anti-depressant-like activity --- an effect that is blocked by the AMPA receptor antagonist NBQX and the serotonin (5-HT) receptor subtype 5-HT1A antagonist WAY-100635. It also increases glutamate and serotonin levels and the expression of c-Fos in the dorsal raphe nucleus. It also impairs memory acquisition, consolidation, and retrieval.
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DC36248 (+)-Pinoresinol
(+)-Pinoresinol is a lignan that diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase. (+)-Pinoresinol scavenges ABTS but not 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in cell-free assays. It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37 cells. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells and inhibits LPS-induced nitric oxide production in RAW 264.7 cells.
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DC36218 Aminacrine hydrochloride monohydrate
Aminacrine hydrochloride monohydrate is a highly fluorescent anti-infective dye used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.
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DC36145 AI3-63211
Caffeic acid provides protection against genotoxicity of DMBA.
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DC36112 L2-b
L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.
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DC36100 Actosin
Cyclocumarol is an anticoagulant similar to but less potent than warfarin. This product may cause hemorrhaging if used indiscriminately.
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DC36088 7-Geranyloxycoumarin
Aurapten is a coumarin with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. Aurapten may also be useful in the treatment of Alzheimer’s disease by inhibiting β-secretase (BACE1) activity.
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DC36085 3S,5S-Atorvastatin
ent-Atorvastatin is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor
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DC36073 (+)-ar-Turmerone
ar-Turmerone is an immunomodulator which has exhibited cytotoxicity toward various cell lines such as the K562, L1210, U937 and RBL-2H3 cell lines.
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DC36065 Apovincamine
Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, a derivative of Vincamine with vasodilating activity.
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DC36064 Allylisopropylacetylurea
Apronalide, also known as Allylisopropylacetylurea or Apronal, is a hypnotic/sedative drug of the ureide (acylurea) group which may induce cytochrome P-450 through barbiturate-like activity. Though it is not a barbiturate, apronalide is similar in structure and action to the barbiturates, although considerably milder in comparison. Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use except in Japan.
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DC36052 (-)-Alkannin
Alkannin is an antioxidant. It is also known to have wound healing, antitumor, and antithrombotic properties.
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DC36030 Alcophosphamide
Alcophosphamide is a urinary metabolite of cyclophosphamide which may be used in proteomics research.
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DC35924 PEG3-bis(phosphonic acid diethyl ester)
PEG3-bis(phosphonic acid diethyl ester) is a PEG Linker.
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DC35871 m-PEG3-succinimidyl carbonate
m-PEG3-succinimidyl carbonate is a PEG Linker.
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DC35816 Mal-PEG6-t-butyl ester
Mal-PEG6-t-butyl ester is a PEG derivative containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35815 Mal-PEG4-t-butyl ester
Mal-PEG4-t-butyl ester is a PEG derivative containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35813 Mal-PEG2-t-butyl ester
Mal-PEG2-t-butyl ester is a PEG derivative containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35798 Mal-PEG6-acid
Mal-PEG6-acid is a PEG derivative containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35796 Mal-PEG4-acid
Mal-PEG4-acid is a PEG derivative containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35613 Hexane-1
Hexane-1,6-diyldiphosphonic acid is a non-PEG crosslinker.
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