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Cat. No. Product Name Field of Application Chemical Structure
DC36522 Barium lithol red
Barium lithol red is also known as PR-258, is a transparent blue shade red pigment with low viscosity and excellent tinting strength. Lithol red is an azo pigment8 that comprises a family of sodium (PR 49), barium (PR 49:1), calcium (PR 49:2), and strontium (PR 49:3) salts of diazotised Tobias (2-naphthylamine-1-sulfonic) acid coupled with 2-naphthol. The metal dictates the shade of the pigment, which ranges from yellow to purplish blue.
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DC36488 3,5-Diiodo-L-thyronine
3,5-Diiodo-L-thyronine, Iodinated thyronine hormone. regulating gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.
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DC36447 N-methyl Paroxetine
N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes. It inhibits serotonin (5-HT) uptake in rat brain synaptosomes and has been used as a precursor in the synthesis of paroxetine.
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DC36382 16-Deethylindanomycin
Deethylindanomycin is a polyether antibiotic that is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae. It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when. Deethylindanomycin acts as an ionophore in lipid bilayer membranes and is more selective for potassium ions than calcium, magnesium, and sodium ions. It induces histamine release from rodent mast cells and human basophils in vitro in a calcium-dependent manner.
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DC36362 Boc-Leu-Arg-Arg-AMC
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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DC36344 Desacetyl cefapirin
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin. Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus.
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DC36331 Siquil
Triflupromazine is a phenothiazine that binds to muscarinic receptors and inhibits serotonin (5-HT) uptake by synaptosomes. Formulations containing triflupromazine were previously used as antipsychotics.
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DC36330 NSC 33700
γ-Valerolactone is a prodrug form of γ-hydroxyvaleric acid.
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DC36294 6(5H)-Phenanthridinone
6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimental autoimmune encephalomyelitis (EAE). It also decreases serum levels of lactate dehydrogenase as well as hepatic lipid peroxidation, oxidative DNA damage, and PARP levels.
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DC36286 Dihydrocaffeic acid
Dihydrocaffeic acid is a polyphenol with antioxidant, neuroprotective, and enzyme inhibitory properties. Dihydrocaffeic acid scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and increases the survival of RGC-5 mouse retinal ganglion cells under hypoxic conditions and in the presence of S-nitroso-N-acetyl-D,L-penicillamine (SNAP). It also decreases endothelial nitric oxide synthase (eNOS) activity and decreases infarct size in a rat model of transient ischemia induced by middle cerebral artery occlusion (MCAO).
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DC36210 Amigal
Migalastat is a potent inhibitor of glycolipid biosynthesis.
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DC36199 (+)-Amlodipine
(R)-Amlodipine is the R isomer of Amlodipine --- a medication used to lower blood pressure and prevent chest pain.
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DC36163 AI3-52333
Gibbs reagent is a universal thin-layer chromatographic visualization reagent.
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DC36147 Triphenyltetrazolium bromide
Triphenyltetrazolium bromide may be useful in the detection of experimental cerebral infarction and biochemical analysis.
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DC36134 Thioperamide
Thioperamide is an HRH4 antagonist and selective HRH3 antagonist capable of crossing the blood–brain barrier. Thioperamide negatively regulates the release of histamine and enhances the activity of histaminergic neurons by blocking autoreceptors. Its action on H3 is thought to promote wakefulness and improve memory consolidation.
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DC36116 AG-1777
Lansoprazole sulfide is an impurity of Lansoprazole -- a gastric pump inhibitor.
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DC36110 IMS2186
IMS2186 is an anti-proliferative and anti-angiogenic agent. IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss.
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DC36102 Aciclovir EP Impurity F
N2-Acetylaciclovir, also known as Aciclovir EP Impurity F, is an impurity of Aciclovir.
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DC36056 Aminoform
Methenamine is an anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH.
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DC35960 Ms-PEG8-Ms
Ms-PEG8-Ms is a PEG Linker.
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DC35926 PEG5-bis(phosphonic acid diethyl ester)
PEG5-bis(phosphonic acid diethyl ester) is a PEG Linker.
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DC35921 Propargyl-PEG3-phosphonic acid ethyl ester
Propargyl-PEG3-phosphonic acid ethyl ester is a PEG Linker.
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DC35873 m-PEG5-succinimidyl carbonate
m-PEG5-succinimidyl carbonate is a PEG Linker.
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DC35848 Bis-Mal-PEG3
Bis-Mal-PEG3 is a PEG derivative containing a two maleimide groups. The maleimide groups will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35700 Azido-PEG3-CH2CO2-NHS
Azido-PEG3-CH2CO2-NHS is a PEG Linker.
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DC35680 Ald-CH2-PEG3-azide
Ald-CH2-PEG3-azide is a crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. The aldehyde group reacts with amines and the N-terminal of peptides and proteins to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.
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DC35629 Sulfo-NHS
Sulfo-NHS is a chemical modification reagent for converting carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods.
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DC35617 diethyl 7-bromoheptylphosphonate
diethyl 7-bromoheptylphosphonate is a PEG Linker.
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DC35589 m-PEG3-4-nitrophenyl carbonate
m-PEG3-4-nitrophenyl carbonate is a PEG derivative.
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DC35579 m-PEG13-Ms
m-PEG13-Ms is a PEG Linker
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