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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC34562 NHNB
NHNB is a selective inhibitor of histone deacetylases-8 (HDAC8). NHNB provides the most potent CE4 inhibitor reported to date.
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DC34548 Nothofagin
Nothofagin is a natural anti-oxidant which inhibits endothelial protein C receptor (EPCR) shedding. Nothofagin shows diuretic, natriuretic, and potassium-sparing effects associated with prostanoids generation and muscarinic receptor activation.
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DC34496 Lumiflavin
Lumiflavine is a riboflavin uptake inhibitor. Lumiflavine is produced by the photolysis of vitamin B2 (Riboflavin).
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DC34441 Epigenetic Multiple Ligand
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
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DC34423 AC-93253 iodide
AC-93253 iodide is a SIRT2 selective inhibitor. It acts by significantly enhancing acetylation of tubulin, p53, and histone H4.
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DC34341 CAY10589
CAY10589 is an inhibitor of mPGES-1.
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DC34321 MK6-83
MK6-83 is an agonist of the transient receptor potential channel ML3 (TRPML3).
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DC34299 TT01001
TT01001 is a mitoNEET ligand. It acts by improving diabetes and ameliorates mitochondrial function in db/db mice.
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DC34264 KS370G
KS370G is an inhibitor of UUO-induced renal fibrosis markers expression. It acts by attenuating collagen deposition in the obstructed kidney and significantly lowering the expression of renal inflammatory chemokines/adhesion molecules and monocyte cells marker.
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DC34231 S32826
S32826 is an inhibitor of autotaxin.
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DC34205 5HPP-33
5HPP-33 is an antiproliferative and antimitotic microtubule-stabilizer.
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DC34203 Atractyloside Potassium Salt
Atractyloside Potassium Salt is a natural inhibitor of ADP and ATP transport (AAT). It acts by binding specifically to the adenine nucleotide translocator in the inner mitochondrial membrane.
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DC34181 Y198561
Barnidipine Hydrochloride is a long-acting calcium channel blocker.
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DC34175 CAPE
CAPE is an inhibitor of BAF. It works by activating latent HIV-1, inhibiting PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK), hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
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DC34170 5-Methyltryptamine hydrochloride
5-Methyltryptamine hydrochloride acts as a 5-HT receptor agonist.
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DC34164 Hyodeoxycholic acid sodium salt
Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein (HDL) function, reduces farnesoid X receptor antagonist bile acids and the gene expression levels of sterol regulatory element binding protein 1c, acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase-1, and induces strong cytotoxicity, apoptosis and IL-8 synthesis.
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DC34145 Lomifylline
Lomifylline is an inducer of Ca2±release from intracellular stores via the ryanodine receptor.
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DC34144 Temafloxacin
Temafloxacin is an antibiotic and antimycobacterial agent. It was approved to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections in 1992.
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DC34103 NAAD sodium salt
NAAD sodium salt initiates intracellular Ca2+ release by a cyclic ADP ribose-independent and IP3 mechanism. It is also used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS).
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DC34090 BIX
BIX is a BiP (Hsp70-5) ER chaperone inducer. BIX induces BiP expression in vitro and in vivo. Protects against ER-stress induced cell death in neuronal and retinal cell lines.
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DC34013 Benzoctamine Hydrochloride
Benzoctamine is a drug that possesses sedative and anxiolytic properties. Medically, benzoctamine is used as a treatment for anxious outpatients to control aggression, enuresis, fear, and minor social maladjustment in children.
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DC34000 PEG4 diazide
PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by Click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.
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DC33930 Cyanine3 carboxylic acid
Free Cyanine3 carboxylic acid (Cy3? carboxylic acid analog), non-activated dye. Non-sulfonated reagent, with good solubility in organic solvents, and limited aquous solubility. The dye can be used as a non-reactive fluorophore, for control experiments, and for calibration.
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DC33832 Butyric acid
Butyric acid is a flavor and fragrance agent.
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DC33824 Cyanuric acid
Cyanuric acid is a chlorine stabilizer. It is a precursor to N-chlorinated cyanurates, which are used to disinfect water and crosslink agents for polyurethane resins.
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DC33804 Isethionic acid
Isethionic acid is a major metabolite in F. cylindrus. It is a organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. It is a water-soluble liquid used in the manufacture of mild, biodegradable, and high-foaming anionic surfactants.
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DC33800 Zaldaride maleate
Zaldaride maleate is an intestinal calmodulin inhibitor which has been shown to decrease the severity and duration of travelers' diarrhea and research suggests that calmodulin and intracellular calcium may serve as mediators of diarrhea in bacterial enteric infection.
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DC33797 Cotarnine chloride
Cotarnine chloride is a oxidative degradation product of the drug Noscapine.
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DC33791 Strophanthin
Strophanthin inhibits free-radical oxidation of o-dianisidine via binding to the enzyme-substrate complex, preventing the generation of a stable semi-oxidized product of o-dianisidine, and thus inhibiting the enzyme by the anticompetitive mechanism. Mechanisms of oxidation of slowly and rapidly oxidizable substrates of peroxidase in the presence of strophanthin G are suggested.
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DC33775 Kifunensine
Kifunensine is potent and selective inhibitor of class I α-mannosidases and may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory action leads to the high mannose glycoproteins in cell culture.
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