Potent and selective inhibitor of NTPDase1

Potent and selective inhibitor of NTPDase1

Building block for syntheses of 8-BuS-AMP, ADP, ATP, and c-AMP

Novel activator of cAMP-dependent protein kinase (PKA) with high selectivity for site B-I of PKA

Carcinogenic adduct, covalently binding DNA bases and promoting mutagenesis near the adduct site

Novel tumor-targeting NIR fluorophore-conjugated hypoxic tumor inhibitor, preferentially accumulating in hypoxic tumor cells, sensitively outlining the tumor contour, and effectively inhibiting tumor growth synergistically by chemotherapy and radiotherapy

Precursor of paclitaxel, a anti-tumor agent

Potent dual PKCθ/δ inhibitor, efficiently inhibiting tumor growth in pancreatic cancer (PC) by inducing cellular apoptosis and suppressing the NF-κB/p-P65 pathway

Potent and selective calcium sensing receptor agonist

Non-selective NOS inhibitor

Potent inhibitor of AChE in treatment of cognitive manifestation of AD

Natural hypoxia-inducible factor-1α (HIF-1α) inhibitor, targeting the protein activity which could stabilize HIF-1α

Fluorescent amino acid for protein labeling

Novel Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist, Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells

Useful pharmaceutical building block

Ligand binding to the orthosteric site of D2 receptor

Natural antiplasmodial agent

Novel NIR fluorescent heptamethine cyanine dye IR-780 and 5FU conjugate, exhibiting enhanced CSCs-targeting therapeutic effects

Agonist of tyrosine receptor kinase B (TrkB)

Novel potent cell growth inhibitor, suppressing the cytokine-Induced β-cell apoptosis

Glucocorticoid with anti-inflammatory and immunosuppressive activities

Thiopurine metabolite, blocking activation of GTPase Rac1 in T lymphocytes

Novel potent inhibitor of chikungunya virus (CHIKV) replication

Novel inhibitor of 6-phosphogluconate dehydrogenase (6PGD)

The precursor for preparing 11C-PiB, a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis

Metabolite of soy isoflavone, preventing bone loss and reversing the unfavorable changes of lipid metabolism

Novel highly potent agonist of GPR84

Novel high-affinity NR5A probe for fluorescence polarization competition assays, tightly binding the NR5A receptors and detecting direct binding of synthetic and phospholipid ligands

Selective agonist of protein kinase A, strongly preferring the A site of cAK II

Novel cationic antimicrobial peptide (CAP)