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PROTACs

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Cat. No. Product Name Field of Application Chemical Structure
DC67768 tert-Butyl (14-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)-14-oxo-3,6,9,12-tetraoxatetradecyl)carbamate Featured
DC67770 (S,R,S)-AHPC-C5-COOH Featured
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases.
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DC67771 (2S,4R)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide hydrochloride Featured
DC67772 tert-butyl (2S)-2-(cyanomethyl)-4-(2-methylsulfanyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazine-1-carboxylate Featured
DC67774 2-(4-Chloro-phenylamino)-thiazole-4-carboxylic acid Featured
DC67779 (E)-3-(3,4-DIMETHOXYPHENYL)-1-(3-HYDROXYPHENYL)-1-PROPENONE Featured
DC67780 Thalidomide acid Featured
Thalidomide acid is a Thalidomide analog that can be useful in PROTAC research.
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DC67790 Benzoic acid, 4-chloro-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)- Featured
DC67787 4-BROMO PHTHALIC ANHYDRUS Featured
DC67792 Benzonitrile, 4-(4-methyl-5-thiazolyl)-2-(phenylmethoxy)- Featured
DC67797 5-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Featured
DC67801 6-amino-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide Featured
DC67800 5-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Featured
DC67802 Pomalidomide-PEG4-C2-NH2 hydrochloride Featured
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs.
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DC67803 Thalidomide-NH-C10-COOH Featured
Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology.
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DC67806 Thalidomide-5-NH-PEG2-C2-COO(t-Bu) Featured
DC67809 Pomalidomide-5-C8-NH2 hydrochloride Featured
Pomalidomide-5-C8-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
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DC67811 Pomalidomide-5-C6-NH2 hydrochloride Featured
Pomalidomide-5-C6-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
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DC48434 TD-165 Featured
TD165(TD 165) is a PROTAC-based cereblon (CRBN) degrader that degrads Cav1.2α with the DC50 of 20.4 nM, comprising a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.
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DC67820 6-Bromo-indole-1,4-dicarboxylic acid 1-tert-butyl ester 4-methyl ester Featured
DC67824 (S,R,S)-AHPC-Me-C-10-NH2 hydrochloride,(S,R,S) AHPC Me C10 NH2 hydrochloride,(S,R,S)AHPCMeC10NH2 hydrochloride Featured
DC67825 Undecanamide, 11-amino-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]- Featured
DC67829 1-(Boc-L-tert-leucinyl)-(4S)-4-hydroxy-D-proline Featured
DC67834 1H-Thieno[2,3-e]-1,4-diazepine-3-acetic acid, 5-(4-chlorophenyl)-2,3-dihydro-6,7-diMethyl-2-oxo-, 1,1-diMethylethyl ester, (3S)- Featured
DC67831 2-(aminomethyl)-5-(4-methylthiazol-5-yl)phenol hydrochloride Featured
DC67837 (S)-3-Amino-piperidine-2,6-dione hydrochloride Featured
DC67842 Tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperazine-1-carboxylate Featured
DC67843 6-hydroxy-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid Featured
DC44664 THP-PEG1-alcohol Featured
THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC67753 Thalidomide-O-PEG4-amine Featured
Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
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