19α-Hydroxyasiatic acid|CAS 70868-78-9|DC Chemicals

Cas No.:	70868-78-9
Chemical Name:	19α-Hydroxyasiatic acid
SMILES:	OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)([C@H]([C@@H](C4)O)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Formula:	C₃₀H₄₈O₆
M.Wt:	504.70
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC45486	19α-Hydroxyasiatic acid	19α-Hydroxyasiatic acid, a natural triterpenoid, possesses anti-elastase activity.
DC41120	AE-3763	AE-3763 is a peptide-based human neutrophil elastase inhibitor with an IC50 of 29 nM.
DC41083	Freselestat quarterhydrate	Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat quarterhydrate is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat quarterhydrate has a potent anti-inflammatory activity.
DC29003	FK706	FK706 is a potent, slow-binding and competitive inhibitor of human neutrophil elastase with an IC50 of 83 nM and a Ki of 4.2 nM. FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase with IC50s of 22 nM and 100 nM, respectively, and has no inhibitory activity against other serine proteinases such as human pancreatic trypsin, human pancreatic α-chymotrypsin and human leukocyte cathepsin G. FK706 has anti-inflammatory effect.