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AR453588

Cat. No.: DC28743

Chemical Structure

1065609-00-8

For research use only. We do not sell to patients.

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Field of application

AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1065609-00-8
Formula:	C₂₅H₂₅N₇O₂S₂
M.Wt:	519.64
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47198	IHVR-11029	IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM.
DC28983	GKA50	GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose). GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats.
DC28744	AR453588 hydrochloride	AR453588 hydrochloride is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 hydrochloride shows anti-hyperglycemic activity.
DC28743	AR453588	AR453588 is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 shows anti-hyperglycemic activity.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.