Cerdulatinib hydrochloride|CAS 1369761-01-2|DC Chemicals

Cas No.:	1369761-01-2
Chemical Name:	Cerdulatinib HCl
Formula:	C₂₀H₂₈ClN₇O₃S
M.Wt:	482
Sotrage:	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Cat. No.	Product name	Field of application
DC42425	Syk-IN-4	Syk-IN-4 is a potent, selective and orally bioavailable SYK with an IC50 of 0.31 nM. SYK has emerged as a potential target for autoimmunity and hematological cancers.
DC42007	Syk Kinase Peptide Substrate	Syk Kinase Peptide Substrate is a Syk kinase peptide substrate.
DC42006	Syk Kinase Peptide Substrate, Biotin labeled	Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
DC41092	Cerdulatinib hydrochloride	Cerdulatinib hydrochloride (PRT062070) is a selective, oral active and reversible ATP-competitive inhibitor of dual SYK and JAK, with IC50s of 32 nM, 0.5 nM, 12 nM, 6 nM and 8 nM for SYK and Tyk2, JAK1, 2, 3, respectively. Cerdulatinib hydrochloride could be used to research autoimmune disease and B-cell malignancies.
DC40367	Syk-IN-1	Syk-IN-1 (compound 4) is a potent Syk inhibitor, with an IC50 of 35 nM.
DC28255	Lanraplenib succinate	Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.