BAY-885|BAY885|MAPK7 inhibitor

Cas No.:	2307249-33-6
Chemical Name:	(2-amino-4-(trifluoromethoxy)phenyl)(4-(7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl)methanone
Synonyms:	BAY885
SMILES:	C(C1=CC=C(OC(F)(F)F)C=C1N)(N1CCC(C2N=CN=C3C=C(N4CCN(C)CC4)C=NC3=2)CC1)=O
Formula:	C₂₅H₂₈F₃N₇O₂
M.Wt:	515.541
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO

Description:

BAY-885 is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM.

Cat. No.	Product name	Field of application
DC10979	BAY-885	BAY-885 is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM.
DC7242	VX-11e(TCS ERK 11e)	VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-Regulated Kinase); antitumor agent.
DC8384	Sodium Tauroursodeoxycholate (TUDC)	Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
DC7285	FR 180204	Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα.
DC7283	SCH-772984	SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
DC10487	KO947	KO-947 is a small molecule inhibitor of extracellular-signal-regulated kinases 1 and 2 (ERK1/2), as a potential treatment for cancers in which the mitogen activated protein kinase (MAPK) pathway.
DC8866	DEL-22379	DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.