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| Cas No.: | 1611470-23-5 |
| Chemical Name: | 5-(3, 5-dimethoxybenzyloxy)-3-indoleacetic acid |
| Synonyms: | MA-35;MA35;MA 35 |
| SMILES: | N1C2=C(C=C(OCC3=CC(OC)=CC(OC)=C3)C=C2)C(CC(O)=O)=C1 |
| Formula: | C19H19NO5 |
| M.Wt: | 341.36 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model. |