GR 64349 TFA|CAS 0|DC Chemicals

Cas No.:
Chemical Name:	GR 64349 TFA
Synonyms:	KDSFV{Aaa}LM-NH2
Formula:	C₄₄H₆₉F₃N₁₀O₁₃S
M.Wt:	1035.13
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC47011	Elinzanetant	Elinzanetant is a neurokinin receptors antagonist used for the research of Schizophrenia.
DC46851	Imnopitant	Imnopitant is a NK1 receptor antagonist (WO2020132716, compound 1) .
DC42312	Hemokinin 1 (mouse)	Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
DC42311	Neurokinin A TFA	Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.
DC42048	Biotin-Substance P	Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
DC41718	[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA	[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM.
DC41717	[Lys5,MeLeu9,Nle10]-NKA(4-10)	[Lys5,MeLeu9,Nle10]-NKA(4-10) is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM.
DC41716	GR 64349 TFA	GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.
DC41715	GR 94800 TFA	GR 94800 TFA is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively.
DC41714	GR 94800	GR 94800 is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively.