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| Cas No.: | 1638288-31-9 |
| Chemical Name: | Gemcitabine monophosphate disodium salt |
| Synonyms: | Gemcitabine monophosphate disodium salt monohydrate; Gemcitabine monophosphate disodium; GemMP |
| SMILES: | O=C1N=C(N)C=CN1[C@@H]2O[C@H](COP(O[Na])(O[Na])=O)[C@@H](O)C2(F)F.O |
| Formula: | C9H12F2N3Na2O8P |
| M.Wt: | 405.158 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Gemcitabine monophosphate disodium salt, also called GemMP, is a monophosphate derivative of Gemcitabine. Gemcitabine (Gem) is a deoxycytidine analog that is effective against pancreatic cancer and other malignancies following conversion to the 5'-O-mono-, di- and tri-phosphate forms. GemMP decreased tumor cell growth at concentrations ranging from 1 to 50 nM. GemMP is a potent cytotoxic agent that serves to induce apoptosis in association with increased Fas expression in cultured thyroid cancer cell lines. |