- Chemicals for Life Science -

To enhance service speed and avoid tariff delays, we've opened a US warehouse. All US orders ship directly from our US facility.

Home > Inhibitors & Agonists > GPCR > GPR183 (EBI2)

NIBR189

Cat. No.: DC8836 Featured

Chemical Structure

1599432-08-2

For research use only. We do not sell to patients.

We match the best price and quality on market.
Email:order@dcchemicals.com sales@dcchemicals.com
Tel:+86-021-58447131

Get Quotation Now

We are official vendor of:

More than 5000 active chemicals with high quality for research!

Field of application

NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively).

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1599432-08-2
Chemical Name:	(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
Synonyms:	NIBR-189; NIBR 189
SMILES:	BrC1=CC=C(/C=C/C(N2CCN(C(C3=CC=C(OC)C=C3)=O)CC2)=O)C=C1
Formula:	C₂₁H₂₁BrN₂O₃
M.Wt:	429.31
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).NIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.

Cat. No.	Product name	Field of application
DC8836	NIBR189	NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively).

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.