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| Cas No.: | 1029044-16-3 |
| Chemical Name: | Pexidartinib (PLX3397) |
| Synonyms: | PLX3397; PLX-3397; PLX 3397; CML-261; CML 261; CML261; FP-113; FP 113; FP113; Pexidartinib; Turalio |
| SMILES: | C1=CC(=NC=C1CC2=CNC3=NC=C(C=C23)Cl)NCC4=CN=C(C=C4)C(F)(F)F |
| Formula: | C20H15ClF3N5 |
| M.Wt: | 417.81 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Pexidartinib (PLX-3397) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13 nM, 27 nM, and 11 nM for CSF1R, c-Kit, and FLT3, respectively. |
| In Vivo: | Pexidartinib is a potent drug for treatment of cancer and used for Phase III TGCT clinical trial[1]. |