QS 11 (QS11,BML-WN117)|supplier DC Chemicals

Cas No.:	944328-88-5
Synonyms:	QS11
SMILES:	OC[C@H](CC1=CC=CC=C1)NC2=C3C(N(CC4=CC=C(C5=CC=CC=C5)C=C4)C=N3)=NC(OC6=CC=C(CCC7)C7=C6)=N2
Formula:	C₃₆H₃₃N₅O₂
M.Wt:	567.68
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.For the detailed information of QS 11 (QS11,BML-WN117), the solubility of QS 11 (QS11,BML-WN117) in water, the solubility of QS 11 (QS11,BML-WN117) in DMSO, the solubility of QS 11 (QS11,BML-WN117) in PBS buffer, the animal experiment (test) of QS 11 (QS11,BML-WN117), the cell expriment (test) of QS 11 (QS11,BML-WN117), the in vivo, in vitro and clinical trial test of QS 11 (QS11,BML-WN117), the EC50, IC50,and Affinity of QS 11 (QS11,BML-WN117), Please contact DC Chemicals.

Cat. No.	Product name	Field of application
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DC11132	Wnt-p53 inhibitor compound 2	Wnt-p53 inhibitor compound 2 is a novel inhibitor targets both Wnt signaling and ATM/p53, potently inhibits Wnt transcription (IC50=11 nM) and p53 transcription (EC50=1.9 nM).
DC5139	QS 11 (QS11,BML-WN117)	QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor.
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