COX-1 Inhibitor IV（TFAP）

Cas No.:	1011244-68-0
Chemical Name:	N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
SMILES:	C1=CC(=CC=C1C(=O)NC2=NC=C(C=C2)N)C(F)(F)F
Formula:	C₁₃H₁₀F₃N₃O
M.Wt:	281.23
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
Target:	COX-1:0.8 μM (IC50) Human Endogenous Metabolite
In Vitro:	TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.
References:	[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

Cat. No.	Product name	Field of application
DC71661	Loxoprofenol-SRS tromethamine	Loxoprofenol-SRS tromethamine (HR1405-01), an active metabolite of Loxoprofen, is a Safe intravenous non-steroidal anti-inflammatory drug (NSAID) with superior anti-inflammatory and analgesic activities.
DC11263	COX-1 Inhibitor IV（TFAP）	The COX-1 Inhibitor IV, TFAP controls the biological activity of COX-1.
DC8806	NS-398	NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2).
DC7112	FK 3311	FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent.