THI0019|CAS 1378532-99-0|DC Chemicals

Cas No.:	1378532-99-0
Chemical Name:	THI0019
Synonyms:	THI0019;triazadodecanoic acid methyl ester
SMILES:	S1C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])S1)C(=O)OC([H])([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])C(N([H])[C@@]([H])(C([H])([H])C(=O)OC([H])([H])[H])C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])O2)=O
Formula:	C₂₉H₃₅N₃O₇S₂
M.Wt:	601.7341
Purity:	>98%
Sotrage:	Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month

Cat. No.	Product name	Field of application
DC73236	GSK3335103	GSK3335103 is a highly potent and orally bioavailable nonpeptidic αvβ6 integrin inhibitor with pIC50 of 8.0. GSK3335103 shows high desirable oral pharmacokinetic profiles in rat, dog, and minipig, with low to moderate clearance, moderate volumes of distributio, high to complete oral bioavailabilities and high solubility in all physiological media.
DC40247	THI0019	THI0019 represents a novel class of integrin modulators with unique agonist activity targeting multiple adhesion receptors.
DC9487	Arg-Gly-Asp-Ser	Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS