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| Cas No.: | 150915-40-5 |
| Chemical Name: | Tirofiban HCl hydrate |
| Synonyms: | Aggrastat; L 700462; L-700,462; MK-383; MK 383; MK383; Tirofiban; Tirofiban hydrochloride monohydrate. |
| SMILES: | O=S(N[C@@H](CC(C=C1)=CC=C1OCCCCC2CCNCC2)C(O)=O)(CCCC)=O.Cl.O |
| Formula: | C22H39ClN2O6S |
| M.Wt: | 495.072 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonistTirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation. Tirofiban is an antithrombotic used in the treatment of unstable angina.Tirofiban, in a concentration-dependent manner reduced platelet aggregation evoked by ADP (IC50 approximately 70 ng/ml), collagen (IC50 approximately 200 ng/ml), and thrombin (IC50 approximately 5,000 ng/ml). |