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CP-LC-1422

Cat. No.: DC67460

Chemical Structure

For research use only. We do not sell to patients.

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Field of application

Derived from the natural amino acid homocysteine, CP-LC-1422 is an ionizable cationic lipid that enables robust in vivo delivery of various RNA forms (mRNA, cRNA, and saRNA), driving high protein expression. When formulated into LNPs (50/38.5/10/1.5 molar ratio of ionizable lipid/cholesterol/DOPE/PEG-lipid), it achieves superior spleen-specific targeting compared to commercial options through intravenous administration, while maintaining an excellent safety profile.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:
Chemical Name:	CP-LC-1422
Synonyms:	CPLC1422， CP LC 1422
SMILES:	O=C(NCCN(C)C)C(CCSCCC(OCCCCCCCC(C)C)=O)NC(CCCCC(CCSCCC(OCCCCCC(C)C)=O)SCCC(OCCCCCC(C)C)=O)=O
Formula:	C₅₁H₉₇N₃O₈S₃
M.Wt:	976.5
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC67460	CP-LC-1422	Derived from the natural amino acid homocysteine, CP-LC-1422 is an ionizable cationic lipid that enables robust in vivo delivery of various RNA forms (mRNA, cRNA, and saRNA), driving high protein expression. When formulated into LNPs (50/38.5/10/1.5 molar ratio of ionizable lipid/cholesterol/DOPE/PEG-lipid), it achieves superior spleen-specific targeting compared to commercial options through intravenous administration, while maintaining an excellent safety profile.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.