FX2149|CAS 1842427-90-0|DC Chemicals

Cas No.:	1842427-90-0
Chemical Name:	Benzamide, N-propyl-3-[(3-pyridinylsulfonyl)amino]-
Synonyms:	Benzamide, N-propyl-3-[(3-pyridinylsulfonyl)amino]-
SMILES:	C(NCCC)(=O)C1=CC=CC(NS(C2=CC=CN=C2)(=O)=O)=C1
Formula:	C₁₅H₁₇N₃O₃S
M.Wt:	319.37878203392
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC73146	MK-1468	MK-1468 is a potent, selective, brain-penetrant LRRK2 inhibitor with IC50 of 0.4 nM (G2019S LRRK2), potently inhibits the phosphorylation of LRRK2 serine 935 (pSer935) in hPBMCs with IC50 of 2.8 nM.
DC73145	FX2149	FX2149 (FX 2149) is a potent, BBB permeable inhibitor of LRRK2 GTP binding activity with IC90 of 10 nM, reduces PD-linked mutant LRRK2 variants (G2019S and R1441C) that bound with GTP.
DC48117	EB-42486	EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).
DC10360	MLi-2	MLi-2 is an a potent, highly selective, orally available, brain penetrant inhibitor of LRRK2 with an IC50 of 0.76 nM.