miR-21 inhibitor 12|CAS 442522-48-7|DC Chemicals

Cas No.:	442522-48-7
Chemical Name:	miR-21 inhibitor 12
Synonyms:	miR-21-IN-12
SMILES:	COC1=CC=C(OCC(=O)NC2=CC=C(C3=NC4=C(C=CC(Cl)=C4)O3)C=C2)C=C1
Formula:	C₂₂H₁₇ClN₂O₄
M.Wt:	408.838
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC73346	TGP-29b-066	TGP-29b-066 (Targapremir-29b-066) is a specfic small-molecule miR-29b inhibitor that targets miR29b hairpin precursor (pre-miR-29b), selectivity and effectively decreases miR-29b expression levels in C2C12 myoblast, attenuates muscle atrophy in vitro and
DC70599	miR-21 inhibitor 12	miR-21 inhibitor 12 (miR-21-IN-12) is a small molecule inhibitor of microRNA-21 expression and inhibit miR-21 transcription.miR-21-IN-12 inhibited transcription of the miR-21 gene resulting in significant reductions in primary and mature miR-21 levels.miR-21-IN-12 demonstrated cytotoxicity in a cervical cancer cell line via induction of apoptosis and was capable of reducing microtumor formation in a long-term clonogenic assay.miR-21-IN-12 shows some level of selectivity for miR-21 and is not a general miRNA pathway inhibitor.