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NF340

  Cat. No.:  DC71349   Featured
Chemical Structure
202982-98-7
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More than 5000 active chemicals with high quality for research!
Field of application
NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research.
Cas No.: 202982-98-7
Chemical Name: NF 340
Synonyms: NF 340;4,4'-(Carbonylbis(iMino-3,1-(4-Methyl-phenylene)carbonyliMino))bis(naphthalene-2,6-disulfonicacid)tetrasodiuMsalt;AKOS024457821;4,4'-(Carbonylbis(imino-3,1-(4-methyl-phenylene)carbonylimino))bis(naphthalene-2,6-disulfonic acid) tetrasodium salt;Sodium 4,4'-((3,3'-(carbonylbis(azanediyl))bis(4-methylbenzoyl))bis(azanediyl))bis(naphthalene-2,6-disulfonate);Q27087909;DA-56136;202982-98-7;J-013191;tetrasodium;4-[[3-[[5-[(3,7-disulfonatonaphthalen-1-yl)carbamoyl]-2-methylphenyl]carbamoylamino]-4-methylbenzoyl]amino]naphthalene-2,6-disulfonate;EX-A11967
SMILES: S(C1C=C(C2C=C(C=CC=2C=1)S(=O)(=O)[O-])NC(C1C=CC(C)=C(C=1)NC(NC1=C(C)C=CC(=C1)C(NC1=CC(=CC2C=CC(=CC=21)S(=O)(=O)[O-])S(=O)(=O)[O-])=O)=O)=O)(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]
Formula: C37H26N4Na4O15S4
M.Wt: 986.839228153229
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC71349 NF340 NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research.
DC1101 Ticagrelor (Brilinta,AZD6140) Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively.
DC7203 MRS 2578 MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.
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