(+)-JNJ-A07|CAS 2135640-93-4|DC Chemicals

Cas No.:	2135640-93-4
Chemical Name:	(+)-JNJ-A07
Synonyms:	(+)-4-[3-[[1-(4-Chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]butanoic acid;Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-, (+)-
SMILES:	N1(CCC2=C1C=C(C=C2)OC(F)(F)F)C(C(C1=CC=C(C=C1)Cl)NC1=CC(OCCCC(O)=O)=CC(=C1)OC)=O
Formula:	C₂₈H₂₆ClF₃N₂O₆
M.Wt:	578.96
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC49053	(+)-JNJ-A07	(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.
DC48409	AL-611	AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM).