slCeMM1|CAS 949973-22-2|DC Chemicals

Cas No.:	949973-22-2
Chemical Name:	slCeMM1
SMILES:	O=C(NC1=CC2=CC=CC=C2N=C1)CCC3=C(C)N4C(N=C3C)=NC(C(F)(F)F)=N4
Formula:	C₂₀H₁₇F₃N₆O
M.Wt:	414.39

Cat. No.	Product name	Field of application
DC39028	BIA	BIA is a potential TMBIM6 antagonist, prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, and also regulates TMBIM6-leaky Ca2+, further suppressing tumor formation and progression in cancer xenograft models.It is a potential anticancer agent that prevents the binding between mTORC2 and TMBIM6.
DC47562	VB124	VB-124 is a potent and selective MCT4 inhibitor. VB124 might redirect glycolytic carbon flux into mitochondrial pyruvate oxidation. VB 124 bolcks lactate import (IC50=8.6nM), and export (IC50=19nM) in MDA-MB-231 cells that are engineers to express MCT4 as the only major plasma membrane lactate transporter.
DC73701	slCeMM1	slCeMM1 is a potent, highly selective inhibitor of lactate transporter SLC16A3 (MCT4), inhibits intracellular lactate accumulation in SLC16A3 dependent cells (IC50=91 nM).