Tri-SM6.1|CAS 2851077-05-7|DC Chemicals

Cas No.:	2851077-05-7
Chemical Name:	Tri-SM6.1
SMILES:	O=C(NCCOCCOCC1=CN(CCOCCOCCOCCOCCOC2=CC=C(C3=CC=C(C=C3)[C@H](CC(O)=O)NC(CNC(CCCNC4=CC(C)=CC=N4)=O)=O)C5=C2C=CC=C5)N=N1)CCC(CCC(NCCOCCOCC6=CN(CCOCCOCCOCCOCCOC7=CC=C(C8=CC=C(C=C8)[C@H](CC(O)=O)NC(CNC(CCCNC9=CC(C)=CC=N9)=O)=O)C%10=C7C=CC=C%10)N=N6)=O)(CCC(NCCOCCOCC(N=N%11)=CN%11CCOCCOCCOCCOCCOC%12=CC=C(C%13=C%12C=CC=C%13)C%14=CC=C([C@@H](NC(CNC(CCCNC%15=CC(C)=CC=N%15)=O)=O)CC(O)=O)C=C%14)=O)NC(CCCC(O)=O)=O
Formula:	C₁₅₉H₂₀₉N₂₅O₃₉
M.Wt:	3094.5
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC67297	SM6.1 azide (αvβ6 ligand)	SM-6.1 is a small molecule delivery vehicle developed by Arrowhead, targeting αvβ6, which selectively delivers therapeutic siRNA to lung epithelial cells and mediates durable gene silencing post-inhalation.
DC80412	Tri-SM6.1	Tri-SM6.1 is a tridentate small-molecule ligand targeting integrin αvβ6. Tri-SM6.1 binds to integrin αvβ6 on epithelial cells to deliver conjugated α-ENaC RNAi agents。