Wnt/β-catenin agonist 1|CAS 2305372-67-0|DC Chemicals

Cas No.:	2305372-67-0
Chemical Name:	Wnt/beta-catenin agonist 1
Synonyms:	Wnt/;A-catenin agonist 1;Wnt/beta-catenin agonist 1;8-((1,3-Dimethyl-1H-pyrazol-5-yl)methoxy)-5-ethyl-4-methyl-5,6-dihydrophenanthridin-9-ol
SMILES:	O(C([H])([H])C1=C([H])C(C([H])([H])[H])=NN1C([H])([H])[H])C1=C(C([H])=C2C3=C([H])C([H])=C([H])C(C([H])([H])[H])=C3N(C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H])O[H]
Formula:	C₂₂H₂₅N₃O₂
M.Wt:	363.4528
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC46336	Wnt/β-catenin agonist 1	Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM.
DC7053	IWR-1	IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.
DC8489	ETC-159	ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits _beta_-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM.
DC9951	AMBMP	AMBMP hydrochloride is a Wnt canonical signaling activator. Also inhibits tubulin polymerization. Suppresses TLR2/4/5-induced inflammatory response in human monocytes. Inhibits cell proliferation and induces cell cycle arrest in MDA-MB-231 breast cancer c
DC11886	Adavivint	Adavivint (SM-04690, SM 04690, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro