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YSK 05

Cat. No.: DC71417 Featured

Chemical Structure

For research use only. We do not sell to patients.

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Field of application

YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:
Chemical Name:	YSK 05
Synonyms:	Piperidine, 1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-;YSK-05，YSK05
SMILES:	N1(C)CCC(OCCCCCCCC/C=C\C/C=C\CCCCC)(OCCCCCCCC/C=C\C/C=C\CCCCC)CC1
Formula:	C₄₂H₇₇NO₂
M.Wt:	628.07
Purity:	>95%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Sato Y, et al. A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo. J Control Release. 2012 Nov 10;163(3):267-76.

Cat. No.	Product name	Field of application
DC71417	YSK 05	YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.