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Epigenetics

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Cat. No. Product Name Field of Application Chemical Structure
DC11814 cis CM-414
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM).
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DC11815 trans CM-414
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM).
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DC11813 CM-414
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM).
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DC11653 Ischemin
A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
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DC11652 Ischemin sodium
A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
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DC8423 4SC-202 free base
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
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DCR-004 Ellagic acid
>98%,Standard References
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