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Fungal

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Cat. No. Product Name Field of Application Chemical Structure
DC49472 Bis(methylthio)gliotoxin
Bis(methylthio)gliotoxin is a more stable and reliable marker for invasive aspergillosis than gliotoxin and suitable for use in diagnosis.
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DC49471 1233B
1233B is a secondary metabolite from filamentous fungus, Fusarium sp. RK97-94.
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DC49470 BI-10
BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability.
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DC49469 SDH-IN-1
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L).
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DC49468 FBA-IN-1
FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC80 of 1 μg/mL.
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DC49467 CYP51/HDAC-IN-1
CYP51/HDAC-IN-1 is a potent, orally active CYP51/HDAC dual inhibitor. CYP51/HDAC-IN-1 inhibits important virulence factors and down-regulated resistance-associated genes. CYP51/HDAC-IN-1 exhibits potent therapeutic effects for both tropical candidiasis and cryptococcal meningitis.
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DC49466 Viridiol
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity.
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DC49465 Harzianum A
Harzianum A is a trichothecene that isolated from the soil-borne fungus Trichoderma harzianum. Harzianum A shows no cytotoxicity against baby hamster kidney cells, no activity against Gram-negative and Gram-positive bacteria, but modest antifungal activity at 100 μg/mL.
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DC49464 Cladospirone bisepoxide
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations.
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DC49463 N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor and antifungal agent.
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DC49358 1-Phenylsemicarbazide
1-Phenylsemicarbazide is an antifungal agent. 1-Phenylsemicarbazide has the potential for preventing mold growth on industrial products.
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DC49354 Ticlatone
Ticlatone is an antifungal that can be used for the research of mycoses.
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DC49280 32-Desmethylrapamycin
32-Desmethylrapamycin, a rapamycin derivative is an antifungal agent. 32-Desmethylrapamycin is active Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum.
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DC49191 Trichodecenin II
Trichodecenin II is a fungal metabolite that can be found in conidia of the fungus, Trichoderma viride.
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DC49142 Rhamnolipid RL2
Rhamnolipid RL2, is a rhamnolipid, shows antifungal activity.
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DC49093 ent-Heronamide C
ent-Heronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C.
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DC49092 16,17-Dihydroheronamide C
16,17-Dihydroheronamide C has antifungal activity and is designed as probe for the mode-of-action analysis of heronamide C.
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DC48948 Berkeleyacetal C
Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by lipopolysaccharide (LPS). Berkeleyacetal C exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways.
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DC48920 Antibacterial agent 67
Antibacterial agent 67 (IC50 = 0.03 μM) has a great enzyme-inhibiting activity increase toward succinate dehydrogenase in comparison with fluxapyroxad (IC50 = 4.40 μM).
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DC48844 Dendryphiellin D
Dendryphiellin D is a compound isolated from fungus Septoria rudbeckiae, a plant pathogenic fungus isolated from the halophyte Karelinia caspia. Dendryphiellin D significantly inhibits the production of nitric oxide (NO).
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DC48821 (Z)-Fluoxastrobin
(Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens.
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DC48757 Isodihydroauroglaucin
Isodihydroauroglaucin, a fungal metabolite, shows antibacterial activity.
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DC48699 Eucalyptacid A
Eucalyptacid A, an antifungal metabolite, exhibits antifungal activities against Alternaria solani, with MIC values from 6.25 to 50 μM.
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DC48648 (E)-β-Farnesene
(E)-β-Farnesene (trans-β-Farnesene) is a volatile sesquiterpene hydrocarbon which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis.
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DC48603 Chaetosemin J
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM.
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DC48579 Asperfuran
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC50 of 25 μg/ml.
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DC48529 Canadensolide
Canadensolide is an antifungal metabolite of Penicillium canadense.
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DC48528 Anserinone B
Anserinone B is an antifungal and antibacterial benzoquinone. Anserinone B causes radial growth reductions of 50% and 37% against S.fimicola and A. furfuraceus, respectively. Anserinones B also displays moderate cytotoxicity in the NCI’s 60 human tumor cell line panel (GI50=4.4 µg/mL).
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DC48523 Buclosamide
Buclosamide is a topical antimycotic agent.
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DC48520 Monaschromone
Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM.
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