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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC79899 | (E)-RNB-61 |
(E)-RNB-61 is the E configuration of RNB-61. RNB-61 is an orally active cannabinoid CB2 receptor (CB2R) agonist with a Ki range of 0.13 nM to 1.81 nM. RNB-61 has renal protective and/or anti-fibrotic effects.
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| DC79898 | (E)-FOBISIN101 |
(E)-FOBISIN101 is a 14-3-3 protein-protein interaction (14-3-3 protein-protein interaction) inhibitor, with IC50 values of 9.3 and 16.4 μM for disrupting the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively. (E)-FOBISIN101 inhibits the binding of 14-3-3 to Raf-1 and proline-rich AKT substrate, and neutralizes the ability of 14-3-3 to activate exotoxin S ADP-ribosyltransferase. (E)-FOBISIN101 is applicable to 14-3-3-mediated cancer research.
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| DC79897 | (E)-3-Benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide |
(E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide is a chemically synthesized flavoring substance and can be found in toothpaste products. (E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide is non-genotoxic, shows no genotoxic activity in bacterial reverse mutation and in vitro mammalian cell micronucleus assays. (E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide does not induce prenatal developmental toxicity in rats.
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| DC79895 | (4S,11R)-DiHDoHE |
(4S,11R)-DiHDoHE is a derivative of Dihydroxy-DHA.
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| DC79894 | (4R,5S)-Nutlin carboxylic acid-NHC2-PEG2-N3 |
(4R,5S)-Nutlin carboxylic acid-NHC2-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (4R,5S)-Nutlin carboxylic acid based MDM2 ligand and a linker used in PROTAC technology. (4R,5S)-Nutlin carboxylic acid-NHC2-PEG1-N3 can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-30.
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| DC79893 | (4R,5S)-Nutlin carboxylic acid-NHC2-PEG1-N3 |
(4R,5S)-Nutlin carboxylic acid-NHC2-PEG1-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (4R,5S)-Nutlin carboxylic acid based MDM2 ligand and a linker used in PROTAC technology. (4R,5S)-Nutlin carboxylic acid-NHC2-PEG1-N3 can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-29.
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| DC79891 | (3S,5S)-3,5-Diaminohexanoate |
(3S,5S)-3,5-Diaminohexanoate ((3S,5S)-DAH) is a nucleoside metabolite.
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| DC79890 | (3S)Lenalidomide-5-methylpiperazine benzenesulfonate |
(3S)Lenalidomide-5-methylpiperazine benzenesulfonate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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| DC79889 | (2Z,4E)-5-Hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid |
(2Z,4E)-5-Hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid is a 5-hydroxypenta-2,4-diene-1,2,5-tricarboxylic acid.
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| DC79888 | (2S,3S)-Zenidolol hydrochloride |
(2S,3S)-Zenidolol ((2S,3S)-ICI-118551) hydrochloride is a β2-adrenergic receptor (β2AR) antagonist with pKi values for β1AR and β2AR of 7.51 and 9.27 respectively. (2S,3S)-Zenidolol hydrochloride can be used in the research of heart failure, ischemic heart disease and hypertension.
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| DC79887 | (2S)-2-Isopropyl-3-oxosuccinate |
(2S)-2-Isopropyl-3-oxosuccinate ((2S)-2-Isopropyl-3-oxosuccinic acid) is a nucleoside metabolite.
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| DC79886 | (2S)-2-Amino-5-(2-amino-5-hydro-5-methyl-4-imi-dazolon-1-yl)pentanoic acid |
(2S)-2-Amino-5-(2-amino-5-hydro-5-methyl-4-imi-dazolon-1-yl)pentanoic acid is an amino acid derivative.
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| DC79885 | (2R,3S,4R,5R)-GlcAc-GlcA |
(2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative that can be used in the synthesis of ADC linkers.
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| DC79884 | (25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA |
(25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA is a nucleoside metabolite.
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| DC79883 | (25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA |
(25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA is a coenzyme A derivative.
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| DC79882 | (21R)-Argatroban |
(21R)-Argatroban is a diastereoisomer of Argatroban. (21R)-Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R)-Argatroban can be used for research related to anticoagulation.
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| DC79881 | (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride |
(2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride (compound 1AA) is a SETBP1 inhibitor that disrupts the interaction between SETBP1 and XPO1. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride inhibits colony formation, induces differentiation/cytotoxicity, and downregulates the transcription of Setbpl target genes. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride improves survival and reduces the spleen size of leukemic mice. (2-(β-Piperidinoethyl)-9-hydroxyellipticinium chloride can be used for myeloid neoplasms and solid tumors research.
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| DC79880 | (1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester |
(1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester ((1S,3S)-Benzyl-3-hydroxycyclopentanecarboxylate) is a synthetic intermediate. (1S,3S)-3-Hydroxycyclopentane carboxylic acid benzyl ester is useful for pharmaceutical synthesis.
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| DC79879 | (1R,9S)-Dxd |
(1R,9S)-Dxd is an isomer of (Dxd). (1R,9S)-Dxd is an ADC payload that can be used in the synthesis of ADCs (antibody-drug conjugates).
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| DC79877 | (1R)-KRAS inhibitor-24 |
(1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R.
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| DC79875 | (±)-Homoproline |
(±)-Homoproline (2-Pyrrolidineacetic acid) is the precursor for the biosynthesis of Tussilagine and Isotussilagine. (±)-Homoproline can be used in neurological research.
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| DC79874 | (+)-trans-Limonene oxide |
(+)-trans-Limonene oxide is an antimicrobial essential oil component with activity against Staphylococcus aureus. (+)-trans-Limonene oxide acts as a selective agent for drug-resistant bacterial mutants without increasing the mutation frequency of Staphylococcus aureus USA300. (+)-trans-Limonene oxide can be used in studies of Staphylococcus aureus infection.
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| DC79873 | (+)-Sclareol oxide |
(+)-Sclareol oxide is a compound that can be isolated from essential oils of Salvia sclarea. (+)-Sclareol oxide can be used in synthesis of puupehenone-related bioactive metabolites.
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| DC79872 | (+)-Adlumine |
(+)-Adlumine (O-Methylcorledine) is an alkaloid derivative found in Corydalis ledebouriana.
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| DC79871 | (-)-P7C3-S243 |
(-)-P7C3-S243 is an orally active, blood-brain barrier permeable neuroprotective agent. (-)-P7C3-S243 binds to μ-opioid Receptor and TSPO. (-)-P7C3-S243 inhibits the premature apoptosis death of newborn hippocampal neurons, protects mature nigral dopaminergic neurons, promotes neuronal survival and prevents cognitive impairment. (-)-P7C3-S243 ameliorates depression-like behaviors in rat models. (-)-P7C3-S243 is applicable to research related to Parkinson's disease and Alzheimer's disease.
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| DC79870 | (-)-IHCH7041 |
(-)-IHCH7041 (Compound (-)-(S)-I-10) is a selective and orally active dopamine D2 receptor agonist with a Ki of 22.44 nM. (-)-IHCH7041 can activate Gαi1 protein and β-arrestin2 signaling pathway with EC50 values of 1.38 and 2.75 nM. (-)-IHCH7041 can improve cognitive impairment and memory capacity. (-)-IHCH7041 can be used for the research of neurological disease, such as Alzheimer's disease.
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| DC77926 | Litenimod sodium |
Litenimod sodium is potent type B agonist of toll Like receptor 9 (TLR9), triggering both innate and adaptive immune response.
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| DC77925 | Lexaptepid Pegol |
Lexaptepid Pegol is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
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| DC77924 | Lexaptepid Pegol sodium |
Lexaptepid Pegol sodium is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
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| DC77923 | ISIS 1082 |
ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
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