Natural selective estrogen receptor modulator, showing higher binding affinity to ER-β than ER-α with both estrogenic and antiestrogenic effects depending on the E2 concentration

Selectiveγ‑Aminobutyric Acid(C) (GABAC) Antagonist

Selectiveγ

Selectiveγ

Natural inhibitor of the autophagy pathway, enhancing immune function, suppressing MAPK and NFκB, showing anti-inflammatory, hypoglycemic, vasorelaxative, and antiproliferative activities

Antioxidant, significantly increased gene expression of the anti-aging factor, SIRT1, stimulating the expression of skin growth factor and inhibiting pro-inflammatory genes

5HT(1B/1D) receptor partial agonist, inhibiting electrically induced plasma extravasation, blocking neurogenic plasma protein extravasation, inhibiting release of calcitonin gene-related peptide

Novel potent and selective triple reuptake inhibitor (TRI)

Potent antagonist of the Pseudomonas aeruginosa Transcriptional Regulator PqsR

Useful building block and intermediate

Natural inhibitor of RORγt, ittenuating Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation

Novel potent and selective anti-Trypanosoma cruzi agent

Novel anticancer pan-JAK inhibitor against A2058 human melanoma cells, selective and potent inhibitor of JAK1 and TYK2

Estradiol derivative, showing antioxidant activity

Antiatherosclerotic, antihyperlipidemic, antiinflammatory, antifungal, antiviral and antineoplastic

Novel plant immunoregulator, being effective in delaying senescence in detached leaves while having low interactions with the cytokinin pathway, upregulating genes involved in processes associated with plant innate immunity such as cell wall remodeling an

Metabotropic glutamate I (mGlu1) receptor antagonist

Potent, ATP-competitive and reversible inhibitor of Akt1/2/3-as1/2 without inhibiting Akt1/2/3-wt

Novel GATA4-NKX2-5 transcriptional synergy activator, significantly enhancing the mechanical stretch-stimulated increase of the ANP mRNA levels

Novel Orally Active Antimalarials Targeting Plasmodium falciparum

Metabolite in the kynurenine pathway, the major route of tryptophan degradation in mammals

Major tryptophan catabolite of the kynurenine pathway, showing antiparasitic activity

Novel plant immunoregulator, being effective in delaying senescence in detached leaves while having low interactions with the cytokinin pathway, upregulating genes involved in processes associated with plant innate immunity such as cell wall remodeling an

Novel potent apoptotic inducer, inducing G2-M cell cycle arrest, blocking tubulin polymerization

Novel mammalian targeting potent inhibitor of rapamycin (mTOR) activation

Biological Active Reagents

Novel anti-Parkinson agent, targeting the D2R

Cell-permeable sialic acid analog, deacetylating intracellularly to a sialyltransferase inhibitor, abolishing SLex expression on HL-60 cells, reducing E-selectin and P-selectin binding and preventing metastasis formation in a mouse lung metastasis model

Novel inhibitor of 3C-like protease (3CLpro) of MERS-CoV and severe acute respiratory syndrome coronavirus (SARS-CoV)

The first-in-class triple topoisomerase I/topoisomerase II/tubulin inhibitor