S3QEL-2 is a modulator of the retrograde signaling. It acts by strongly mitigating the oxidative stress-induced apoptosis that limits the yield of functional ?-cells from intact islets.

PQ1 Succinate is a gap junction enhancer. It acts by restoring GJIC and increasing connexin expression in breast cancer cell lines while not affecting normal mammary cells.

Rhodblock 6 is an inhibitor of the Rho pathway. It acts by specifically abrogating Rho kinase activity.

JMC-4 is a 5-LOX inhibitor.

HNHA is a histone deacetylase (HDAC) inhibitor.

TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).

Ractopamine HCl is a beta-Adrenergic agonist. It acts by being a full agonist at the TAAR1.

8-Oxo-dG is a key biomarker of oxidative stress induced carcinogenesis.

(-)-Sparteine is a natural anticonvulsant. It inhibits seizures, delays the onset of convulsive behavior, and activates the M2 and M4 subtypes of mAChRs.

Droxicam is a non-steroidal anti-inflammatory drug (NSAID) for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.

(S)-Oxiracetam is a positive allosteric modulator of the AMPA receptors.

Tetracaine is a potent local anesthetic. It alters the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores.

Flurbiprofen Axetil, also known as Ropion, is a prodrug of Flurbiprofen that provides better analgesia effects and few side effects.

Nifuroxazide is an antibiotic used for the treatment of colitis and diarrhea in humans and non-humans.

PS372424 HCl is a specific agonist of human CXCR3. It has been shown to induce phosphorylation of ERK and block CXCL11 induced migration of CD45+ cells to air pouches generated on humanized mice.

GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways.

Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall also shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with carboplatin.

UCL2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker. UCL2077 suppresses the sAHP present in hippocampal neurons in culture and in the slice preparation. UCL2077 is selective and has minimal effects on Ca(2+) channels, action potentials, input resistance and the medium afterhyperpolarization.

Inz-1 is a fungal-selective inhibitor of mitochondrial cytochrome bc1.

RBI-257 Maleate is a highly potent dopamine D4 receptor-selective ligand. RBI-257 Maleate may be a useful probe or radioligand for brain dopamine D4 receptors.

ISAM-140 is a potent and highly selective A2B adenosine receptor antagonist.

Coumarin 343 is a blue emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).

TAMRA alkyne for Click chemistry, pure 5-isomer. TAMRA (TMR, tetramethylrhodamine) is a xanthene dye. It forms a FRET pair with fluorescein. This alkyne is suitable for Copper-catalyzed Click chemistry (CuAAC).

Blue emitting Coumarin 343 dye can form a FRET pair with fluorescein (FAM). An amine reactive form, activated NHS ester. This amine-reactive NHS ester contains an aminohexanoyl linker between the fluorophore, and the reactive group. This linker provides better solubility and spatial separation between the fluorophore, and the target molecule being labeled.

2-Iodobenzoic acid is an organic compound and the impact-sensitive intermediate in the synthesis of the Dess-Martin periodinane.

Mecoprop is an herbicide and used to control broadleaf weeds.

2-Acetylnaphthalene is an anticonvulsant/antimicrobial and a fragrance agent. It has a sulfurous type odor and an onion type flavor.

Phenyl ethyl ketone is an aryl ketone. It is a colorless, sweet-smelling liquid that is insoluble in water, but miscible with organic solvents. It is used in the preparation of other compounds.

NCT-14b is a selective HDAC6 inhibitor. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.

Risocaine is a local anesthetic.