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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC35476 THP-PEG8-Tos
THP-PEG8-Tos is a PEG linker. The PEG linker contains 7 units of ethylene glycol.
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DC35474 THP-PEG9
THP-PEG9 is a PEG Linker.
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DC35418 Hydroxy-PEG1-t-butyl ester
Hydroxy-PEG1-t-butyl ester is a PEG derivative containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC35416 Hydroxy-PEG4-CH2CO2H
Hydroxy-PEG4-CH2CO2H, sodium salt, is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35394 Fmoc-NH-PEG11-CH2COOH
Fmoc-NH-PEG11-CH2COOH is a PEG derivative containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC35274 Bis-Tos-(2-hydroxyethyl disulfide)
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35223 Bromo-PEG5-bromide
Bromo-PEG5-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35164 t-Boc-N-Amido-PEG3-azide
t-Boc-N-Amido-PEG3-azide is a PEG derivative containing an azide group and Boc-protected amino group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35137 Bis-PEG2-NHS ester
Bis-PEG2-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).
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DC35136 Bis-PEG1-NHS ester
Bis-PEG1-NHS ester is a PEG derivative containing two NHS ester groups. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35056 Biotin-PEG4-amine
Biotin-PEG4-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The amine group can be coupled to carboxyl groups or 5'phosphate groups to form stable amide bonds. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. Therefore, PEG Linkers can be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34909 Amino-PEG4-amine
Amino-PEG4-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34767 Biotin Hydrazide
Biotin Hydrazide, or Biotin-Hz, is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens.
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DC34761 NHS-LC-Biotin
NHS-LC-Biotin, or Succinimidyl 6-(biotinamido)hexanoate, is an amino-reactive biotinylation reagent with a long spacer arm which helps alleviate steric hindrance. NHS-LC-Biotin is used to biotinylate proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains.
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DC34752 EGS Crosslinker
EGS Crosslinker, or Ethylene glycol bis(succinimidylsuccinate), is a water insoluble homobifunctional crosslinker that can be used to label intracellular proteins. EGS crosslinker is often used in ChIP assays to determine DNA-protein binding interactions.
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DC34748 DSS Crosslinker
DSS crosslinker, or Disuccinimidyl suberate, is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.
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DC34717 Ratic
Ranitidine is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome.
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DC34696 Hydramethylnon
Hydramethylnon is an insecticide primarily used for fire ants. It is poorly absorbed in the mammal body and leaves mostly unchanged.
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DC34677 Esfenvalerate
Esfenvalerate is a common insecticide.
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DC34662 Chromonar hydrochloride
Chromonar hydrochloride is a coronary vasodilator agent. It increases in transmural blood flow.
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DC34650 NCGC00063279
NCGC00063279 is a novel inhibitor of the werner syndrome helicase-nuclease (wrn) helicase
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DC34640 6PNG
6-PNG is a Cav3.2 (T-type) calcium channel blocker.
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DC34637 Rifamycin
Rifamycin is a natural antibiotic which inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, thereby blocking RNA-polymerase transcription initiation.
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DC34528 Micheliolide
Micheliolide is a natural, irreversible activator of pyruvate kinase M2, and a suppressor of leukemia cells.
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DC34516 TD3
TD-3 is an inhibitor of the salt-bridge formation between β-Asp94 and β-His146 hemoglobin (Hb), binding to Hb β-Cys93.
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DC34491 Halofuginone HBr
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
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DC34479 NSC-57969
NSC-57969 is a MDR-selective agent, exhibiting a robust Pgp-dependent toxic activity across diverse cancer cell lines.
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DC34469 Enbucrilate
Enbucrilate is a tissue adhesive, forming polymer films at oil-water interfaces and revealing films of diverse morphology.
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DC34466 Toltrazuril
Toltrazuril (Tol) is a broad-spectrum anticoccidiosis drug that is widely used in the prevention and treatment of coccidiosis infection in poultry and mammals.
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DC34451 HDAC8-IN-2
HDAC8-IN-2 is a selective HDAC8 inhibitor.
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