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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC38051 | Harman |
Harman is a beta-carboline.
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| DC38049 | Lobaric acid |
Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the human recombinant enzyme) and production of 12(S)-HETE (Item No. 34570) by 12(S)-lipoxygenase (IC50 = 28.5 μM). In vivo, lobaric acid (250 μM) decreases lesion number, but not lesion diameter, in tobacco leaves infected with tobacco mosaic virus (TMV).
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| DC38042 | DU-176 |
Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non?–central-nervous-system systemic embolism.
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| DC38040 | Glycolithocholic acid |
Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
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| DC38032 | Meglutol |
Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
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| DC38010 | Lexithromycin |
Lexithromycin is a semi-synthetic antibiotic derived from erythromycin. Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.
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| DC37980 | Lecanoric acid |
Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.
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| DC37952 | Pinaverium bromide |
Pinaverium bromide is a spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic.
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| DC37937 | Cloethocarb |
Cloethocarb is a molluscicide.
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| DC37928 | Maclurin |
Maclurin is isolated from Maclura pomifera. Maclurin is composed of two isoforms (isolectins); some sequence similarity to jacalin; potent non-specific blood-group hemagglutinin.
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| DC37918 | Dequalinium chloride |
Dequalinium chloride is a topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.
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| DC37914 | Vasicinone |
Vasicinone is a quinazoline alkaloid that can be isolated from A. vasica leaves and demonstrates bronchodilatory activity. It also is reported to possess antioxidant activity in nitric oxide and ABTS radical scavenging assays.
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| DC37877 | Ochratoxin C |
Ochratoxin C is a toxic metabolite from Aspergillus orchraceus.
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| DC37871 | Canthaxanthin |
Canthaxanthin is a trans-carotenoid pigment widely distributed in nature. The compound is used as an oral suntanning agent and as a food and drug coloring agent. Oral ingestion of the compound causes canthaxanthin retinopathy.
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| DC37842 | Lypressin |
Lypressin is the porcine antidiuretic hormone (vasopressins). It is a cyclic nonapeptide that differs from arg-vasopressin by one amino acid, containing a lysine at residue 8 instead of an arginine. Lys-vasopressin is used to treat diabetes insipidus or to improve vasomotor tone and blood pressure.
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| DC37823 | Prolylisoleucine |
Prolylisoleucine is a derivative of isoleucine, an α-amino acid that is used in the biosynthesis of proteins.
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| DC37821 | Iditol |
Iditol is a rare sugar alcohol (polyol).
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| DC37795 | Tetrasodium glutamate diacetate |
Tetrasodium glutamate diacetate is a multi-purpose, clear, liquid chelating agent and preservative booster. Tetrasodium Glutamate Diacetate is made from plant material, readily biodegradable, with high solubility over a wide pH range. Tetrasodium Glutamate Diacetate serves the same function in formulations as EDTA, without the health and environmental concerns.
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| DC37784 | Ophthalmic acid |
Ophthalmic acid is a glutathione analog in which cysteine moiety is replaced by L-aminobutyrate.
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| DC37779 | Ergothioneine |
Ergothioneine is a naturally occurring metabolite of HISTIDINE that has antioxidant properties.
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| DC37767 | Felinine |
Felinine is a sulfur-containing amino acid; a major component in the urine of domestic cat.
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| DC37764 | L-Cysteic acid |
L-cysteic acid is an oxidation product of L-cysteine. L-Cysteic acid, an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain, such as those that bind to cysteine sulfinic acid receptors. L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors (mGluRs).
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| DC37744 | Santonin |
Santonin is an Anthelmintic isolated from the dried unexpanded flower heads of Artemisia maritima and other species of Artemisia found principally in Russian and Chinese Turkestan and the Southern Ural region.
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| DC37740 | Lauroyl alanine |
Lauroyl alanine is a fatty acid amide that may be used to support the physical gelation of binary mixtures of aliphatic and aromatic hydrocarbon solvents with potential use in injectable biodegradable drug delivery systems.
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| DC37714 | Elastatinal |
Elastatinal is an elastase inhibitor found in culture filtrates of various species of actinomyces.
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| DC37697 | Levisoprenaline |
Levisoprenaline is a bioactive chemical.
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| DC37662 | Longifolene |
Longifolene is the common (or trivial) chemical name of a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins. The name is derived from that of a pine species from which the compound was isolated, Pinus longifolia (obsolete name for Pinus roxburghii Sarg.)
Chemically, longifolene is a tricyclic sesquiterpene. This molecule is chiral, and the enantiomer commonly found in pines and other higher plants exhibits a positive optical rotation of +42.73°. The other enantiomer (optical rotation ?42.73°) is found in small amounts in certain fungi and liverworts.
Longifolene is used in organic synthesis for the preparation of dilongifolylborane, a chiral hydroborating agent.
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| DC37627 | Jasmone |
Jasmone is an organic compound, which is a volatile portion of the oil from jasmine flowers. It is a colorless to pale yellow liquid. Jasmone can exist in two isomeric forms with differing geometry around the pentenyl double bond, cis-jasmone and trans-jasmone. The natural extract contains only the cis form, while synthetic material is often a mixture of both, with the cis form predominating. Both forms have similar odors and chemical properties.
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| DC37596 | Demethylchlorprothixene |
Demethylchlorprothixene is a bioactive chemical.
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| DC37571 | Chromocarb |
Chromocarb is used to eliminate lipoperoxidation postvitrectomy.
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