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Cat. No. Product Name Field of Application Chemical Structure
DC36732 Benazolin
Benazolin is a synthetically produced chemical compound from the group of thiazolinones (thiazolines with a keto group) or benzothiazolinones. The colorless, crystalline solid is used predominantly as a herbicide agent.
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DC36711 Dechlorogriseofulvin
Dechlorogriseofulvin is a major photoproduct of Griseofulvin.
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DC36705 Deceth-3
Deceth-3 is a non-ionic surfactant.
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DC36693 Decaprenoic acid
Decaprenoic acid is a branched carboxylic acid compound for organic synthesis and proteomics research.
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DC36690 Decanoyllevocarnitine
Decanoyllevocarnitine is an ester derivative of L-carnitine (Cay-21489). It increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid (Cay-90310) in rat hepatocytes.
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DC36659 1,10-dibromo-Decane
Decane, 1,10-dibromo- is used as an alkylating agent and as synthetic organic intermediate.
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DC36653 Henicosafluoro-10-iododecane
Henicosafluoro-10-iododecane is a biochemical.
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DC36645 2-n-Nonyl-1,3-dioxolane
2-n-Nonyl-1,3-dioxolane is a biochemical. It is used as an absorption and penetration enhanceron transdermal.
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DC36625 Decafluorobiphenyl
Decafluorobiphenyl is used as an intermediate in organic synthesis and in pharmaceuticals.
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DC36594 Deacetyldiltiazem
Deacetyldiltiazem is a metabolite product of the drug Diltiazem (a coronary vasodilator), and is present in the plasma of individuals taking that medication.
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DC36593 7alpha-Thiospironolactone
7α-Thio Spironolactone is a Spironolactone (sc-204294) metabolite.
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DC36588 Desacetylcinobufagin
Desacetylcinobufagin is an isoform-specific probe reactions for UGT1A4 and UGT1A3. Also, it is the main urinary metabolite of cinobufagin which potentially cytotoxicity against human hepatoma cells (HepG2) and human leukemia (K562, HL-60) cells.
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DC36532 Bucladesine
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. Bucladesine is a phosphodiesterase inhibitor. Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.
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DC36511 Thiofanox
Thiofanox is a chemical compound used in acaricides and insecticides. Shows potential systemic & contact insecticidal properties against certain phytophagous pests.
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DC36465 Corynecin V
Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
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DC36418 Abacavir carboxylate
Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir. It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.
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DC36414 DiIC1(5)
DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption. It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potential is disrupted. DilC1(5) has been used in combination with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry. It has also been used as a quencher for the detection of serine phosphorylation and tyrosine dephosphorylation post-translational modifications (PTMs) in quenching resonance energy transfer (QRET) and mTR-FRET applications. It displays excitation/emission maxima of 659/666 nm, respectively.
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DC36361 Phloretin-4-O-glucoside
Trilobatin is a dihydrochalcone glucoside and derivative of phloretin that reduces survival of Bel 7402 and HepG2 cancer cells. Trilobatin increases superoxide dismutase (SOD) and glutathione peroxidase (GPX) activity and inhibits lipid peroxidation. Pretreatment with trilobatin reduces hydrogen peroxide-induced cell death and production of mitochondrial reactive oxygen species (ROS), prevents reduction in the mitochondrial membrane potential, and increases the activity of GPX, SOD2, and isocitrate dehydrogenase 2 (IDH2) in PC12 neuronal cells. Trilobatin inhibits infection by various HIV-1 strains without inducing cytotoxicity in target cells.
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DC36338 Biotinyl tyramide
Biotinyl tyramide is a reagent used for tyramide signal amplification (TSA) via catalyzed reporter deposition (CARD). In CARD, a reporter enzyme, such as horseradish peroxidase (HRP) conjugated to a secondary antibody, is bound to the target of interest and catalyzes the covalent deposition of biotinyl tyramide to the sample. The sample is then probed by a detector, such as streptavidin-HRP, allowing detection via chromogenic or fluorescent methods. Biotinyl tyramide has been used in immunohistochemistry, ELISA, Western blot, and in situ hybridization applications.
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DC36327 EATC
EATC is a degradation product of the antibiotic tetracycline. It is active against Pseudomonas, Agrobacterium, Moraxella, Bacillus, and E. coli.
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DC36325 Acetylcimigenol arabinoside
Acetylcimigenol arabinoside is a triterpene glycoside originally isolated from Cimicifuga.
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DC36288 Elaidamide
Elaidamide is a fatty acid amide that has been found in the cerebrospinal fluid (CSF) of sleep-deprived cats. It inhibits rat microsomal epoxide hydrolase. Elaidamide also inhibits porcine pancreatic and human synovial phospholipase A2 (PLA2). In vivo, Elaidamide induces physiological sleep in rats.
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DC36285 A2AR agonist-1
A2AR agonist-1 is an agonist of the adenosine A2A receptor and an inhibitor of equilibrative nucleoside transporter 1 (ENT1). A2AR agonist-1 also rescues motor performance and increases survival in a transgenic mouse model of Huntington’s disease.
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DC36277 GKK1032B
GKK1032B is a fungal metabolite that has antiproliferative and antibacterial activities. GKK1032B inhibits the growth of HeLa S3 cervical and MCF-7 breast cancer cells and Vero cells. It also inhibits the growth of B. subtilis and M. tuberculosis.
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DC36265 3'-O-dephosphono-coenzyme A
3'-O-dephosphono-coenzyme A is an intermediate in the biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5). It is phosphorylated by CoA synthase in humans to form CoA. 3'-Dephosphocoenzyme A can be used as a transcription initiator in the synthesis of CoA-RNA by in vitro transcription.
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DC36263 NSC 112125
TPTZ is a colorimetric reagent commonly used in the detection of iron. TPTZ forms a complex with Fe(II) that can be quantified by colorimetric detection at 594 nm as a measure of iron concentration.
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DC36253 2,5-dimethyl Celecoxib, DMC
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2. It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) and reduces prostaglandin E2 (PGE2) production in HeLa, A549, and HCA-7 cells. It inhibits proliferation of drug-sensitive RPMI8226 and multidrug-resistant 8226/Dox40 multiple myeloma cells, as well as increases the rate of apoptosis when used at concentrations of 20 and 30 μM. 2,5-dimethyl Celecoxib reduces the expression of survivin, cyclin A, cyclin B, MEK1, and MEK2 in 8226/Dox40 cells. The antiproliferative effect of 2,5-dimethyl celecoxib is independent of mPGES-1 inhibition.
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DC36242 Bacopaside II
Bacopaside II is a triterpene glycoside found in B. monnieri that has neuroprotective, anti-angiogenic, and anticancer activities. Bacopaside II decreases hydrogen peroxide-induced intracellular reactive oxygen species (ROS) production and cell death in N2a neuroblastoma cells. Bacopaside II decreases migration and tube formation in 2H11 and 3B11 cells, as well as human umbilical vein endothelial cells (HUVECs) when used at concentrations greater than 15 μM. Bacopaside II inhibits the growth of MDA-MB-231, SHG-44, HCT8, A549, and PC3M cancer cells (IC50s = 32.4, 36.9, 40.3, 44.4, and 45.4 μM, respectively).
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DC36235 A-Peest
Adrenochrome Monoaminoguanidine Mesilate is a chemical compound produced by the oxidation of adrenaline (epinephrine). The derivative carbazochrome is a hemostatic medication.
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DC36232 (S)-2-Aminooctanedioic acid
L-2-Aminosuberic acid is a biochemical.
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