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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC34797 | Propargyl-PEG2-alcohol |
Propargyl-PEG2-alcohol is a PEG derivative containing a hydroxyl group and a propargyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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| DC34739 | SMPH Crosslinker |
SMPH Crosslinker, or Succinimidyl-6-[?-maleimidopropionamido]hexanoate is a water insoluble, heterobifunctional protein crosslinker with a non-cleavable spacer arm length of 14.3 angstroms. The SMPH crosslinking reagent is useful for making antibody drug conjugates (ADCs).
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| DC34736 | SIA Crosslinker |
SIA crosslinker (N-Succinimidyl iodoacetate; NHS-Iodoacetate) is a non-cleavable, heterobifunctional protein crosslinker. The SIA crosslinker reagent is among the shortest amine and sulfhydryl (thiol) reactive protein crosslinkers known with a spacer arm length of 1.5 Angstroms. SIA crosslinker is useful in making antibody drug conjugates (ADCs).
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| DC34735 | SBA Crosslinker |
SBA crosslinker, or N-Succinimidyl bromoacetate, is a sulfhydryl (thiol) and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms. SBA Crosslinker is useful for making antibody drug conjugates (ADCs).
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| DC34709 | Ponceau MX |
Ponceau MX is a dye, which may be used in biochemistry study.
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| DC34652 | HPA-12 |
HPA-12 is a novel potent inhibitor of cert, binding to the ceramide-binding pocket in the cert start domain
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| DC34643 | NSC-175151 |
Cytochalasin E is a natural autophagy inhibitor which enhances chemotherapy-induced cell death. Cytochalasin E is an epoxide-containing analog of Cytochalasin B which potently and selectively inhibits the growth of endothelial cells, thereby impairing angiogenesis and tumor growth. Unlike Cytochalasin A and Cytochalasin B, it does not inhibit glucose transport.
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| DC34610 | BC11 hydrobromide |
BC-11 hydrobromide is an inhibitor of Urokinase-Plasminogen Activator (uPa) which induces additional impairment of mitochondrial activity, the production of reactive oxygen species, and promotion of apoptosis.
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| DC34606 | Ascofuranone |
Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH.
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| DC34576 | TFIIH Modulator19 |
TFIIH Modulator-19 is a small molecule destabilization inducer of the trichothiodystrophy group A protein (TTD-A or p8) dimerization which modulates TFIIH transcriptional activity.
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| DC34522 | DCPP |
DCPP is a potent inhibitor of DHCR7, which is known as the last enzyme in cholesterol biosynthesis.
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| DC34506 | HBX |
HBX is a deubiquitinase inhibitor. It inhibits HAdV type 5 (species C, HAdV-C5) replication and oncogenic transformation through inhibition of the cellular pro-viral factor ubiquitin-specific protease 7 (USP7). HBX also significantly inhibits virus genome replication and progeny release of all adenovirus types tested, with the exception of types 12 and 31, from tested species.
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| DC34502 | SRT647 |
Nicotinamide Riboside is a precursor of NAD+ and a source of vitamin B3 (niacin). Nicotinamide Riboside increases intracellular and mitochondrial NAD+ content in C2C12.
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| DC34486 | Ac4ManNAz |
Ac4ManNAz is a novel probe for metabolic labeling of sialoglycans, selectively imaging polysialic acids in neurons.
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| DC34455 | TP2 |
TP2 is an inhibitor of polyketide synthase 13 (Pks13), preventing synthesis of mycolic acid and resulting in mycobacterial cell death.
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| DC34452 | Aloenin |
Aloenin is a moderate inhibitor of BACE.
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| DC34416 | Cirazoline Hydrochloride |
Cirazoline HCl is a selective alpha1-adrenoceptor agonist and a non-selective imidazoline binding site ligand.
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| DC34408 | EBPC |
EBPC is a potent aldose reductase inhibitor.
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| DC34404 | MDL-12330A |
MDL-12330A is an inhibitor of adenylyl cyclase. It acts by inhibiting cAMP and cGMP phosphodiesterases and blocking slow extracellular and store-operated Ca2+ entry into cells.
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| DC34380 | SMI481 |
SMI481 is the first small-molecule inhibitor of Sec14-like phosphatidylinositol transfer proteins (PITPs).
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| DC34377 | Qc1 |
Qc1 is a reversible, non-competitive inhibitor of threonine dehydrogenase (TDH).
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| DC34360 | DNDS |
DNDS is a voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel blocker.
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| DC34351 | BRD32048 |
BRD32048 is an inhibitor of the ETV1 transcription factor oncoprotein.
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| DC34247 | TLCK hydrochloride |
TLCK hydrochloride is a blocker of the LPS- or cytokine-induced activation of nuclear factor κB (NF-κB).
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| DC34232 | TPCK |
TPCK is a non-specific irreversible inhibitor of serine/cysteine proteases. It acts by inhibiting ScRce1 in the presence of a Ras reporter, but not in the presence of the a-factor peptide.
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| DC34219 | MMV665852 |
MMV665852 is an antischistosomal agent. It has been shown to inhibit worm viability in vitro and reduce worm burden in S. mansoni-infected mice.
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| DC34217 | Proscillaridin |
Proscillaridin, also known as Proscillaridin A, is a cardiotonic glycoside. It potently disrupts topoisomerase I and II activity.
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| DC34174 | DS2 |
DS2 is a selective positive allosteric modulator of d-GABAA receptors.
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| DC34160 | Lithocolic acid |
Lithocolic acid is a bile acid formed from chenodeoxycholate by bacterial action. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
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| DC34123 | Lentinan |
Lentinan is an intravenous anti-tumor polysaccharide and one of the host-mediated anti-cancer drugs which has been shown to affect host defense immune systems.
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