Novel EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis

Novel EGFR inhibitor, significantly reducing myocardial inflammation, fibrosis, apoptosis, and dysfunction, showing promises to the treatment on obesity-induced cardiac complications

Novel EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis

Novel third-generation EGFR tyrosine kinase inhibitor, targeting EGFR T790M mutation in advanced non-small cell lung cancer

Antibiotic, inhibiting bacterial protein synthesis

Natural alpha-aminobutyric acid-rich secondary metabolite of fungi, strongly inhibiting the BBMV V-ATPase, acting as a mitochondrial complex V inhibitor, showing antitumor activity in vivo

Calcium channel blocker, blocking both T-type and L-type calcium channels

Potent agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity

Novel eEF2K inhibitor, inducing significant apoptosis through classical apoptotic pathways

An impurity of Edoxaban, a novel inhibitor of factor Xa

Lipo-pro-prostaglandin E1, preventing hearing disturbance and equilibrium dysfunction due to inner ear microcirculatory disorders

Novel marine-derived anticancer saponin, targeting topoisomerase2alpha by unique interference with its DNA binding and catalytic cycle

Novel specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria

Novel potent specific inhibitor of EcDsbB, targeting disulfide bond forming enzyme

Novel EBV activator, well-performing EBV lytic cycle inducer

Novel dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9, inhibiting Pseudomonas aeruginosa alginate synthesis

Novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties

Novel Oral and Selective Prostaglandin F 2α (PGF 2α ) Receptor Antagonist

Highly potent and selective activator of isozymes CA-VA and CA-VII

Highly potent and selective activator of isozymes CA-VA and CA-VII

Novel degrader of GST-α and GST-α-EGFP fusion proteins as well as endogenous GST-π in cells and lysates

Sigma1 receptor ligand and potential atypical antipsychotic

Novel XIAP BIR2 domain-binding degrader of E3 ubiquitin ligases

Potent Activator of P53-Independent Cellular Senescence

γ-Secretase modulator (GSM) photoaffinity probe, revealing distinct allosteric binding sites on presenilin

Novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through canonical Wnt/β-catenin signaling

Novel potent Inhibitor of PI3Kalpha

Novel Selective and Potent EGFR Inhibitor, Overcoming T790M-Mediated Resistance in Non-Small Cell Lung Cancer

Antitumor antibiotic

Novel allosteric inhibitor of the tumor-promoting interaction between the oncogenic factor AIMP2-DX2 and HSP70