7HP349|CAS 1378535-08-0|DC Chemicals

Cas No.:	1378535-08-0
Chemical Name:	7HP349
Formula:	C₂₈H₃₂N₂O₆S₄
M.Wt:	620.812

Cat. No.	Product name	Field of application
DC73233	Alintegimod (7HP349)	Alintegimod (7HP349) is a small molecule activator of the integrins αLβ2 (LFA-1) and α4β1 (VLA-4). 7HP349 directly activates integrin cell adhesion receptors crucial for the generation of an immune response.
DC48132	Bexotegrast	Bexotegrast is a potent inhibitor of ανβ6 integrin. Bexotegrast can be used for researching fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP) (extracted from patent WO2020210404A1, compound 5).
DC10034	GLPG0187	GLPG0187 is a small molecule integrin receptor antagonist (IRA) with potential antineoplastic activity.
DC7327	Tirofiban(L700462;MK383)	Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.
DC9489	Tirofiban (hydrochloride monohydrate)	Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist
DC8224	Lifitegrast(SAR 1118)	SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye.
DC8399	Cyclo(RGDyK)	Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
DC8055	Cyclo(-RGDfK)	cyclo(-RGDfK,-Arg-Gly-Asp-D-Phe-Lys)) is a selective αvβ3-integrin antagonist.
DC9278	CWHM-12	CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.

Alintegimod (7HP349)