CADD522|CAS 199735-88-1|DC Chemicals

Cas No.:	199735-88-1
Chemical Name:	3-((3,4-dichlorophenyl)carbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
Synonyms:	CADD522; CADD-522; CADD 522;
SMILES:	ClC1=C(Cl)C=CC(NC(C2C(C3)C=CC3C2C(O)=O)=O)=C1
Formula:	C₁₅H₁₃Cl₂NO₃
M.Wt:	326.173
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity[1].
Target:	RUNX2-DNA binding[1]
References:	[1]. Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.

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