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PF-06649298

Cat. No.: DC11967

Chemical Structure

1854061-16-7

For research use only. We do not sell to patients.

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Field of application

A potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1854061-16-7
Chemical Name:	(R)-2-(4-(tert-butyl)phenethyl)-2-hydroxysuccinic acid
Synonyms:	PF 06649298;PF06649298
SMILES:	C(O)(=O)[C@@](CCC1=CC=C(C(C)(C)C)C=C1)(O)CC(O)=O
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM; displays >60-fold selectvity over NaDC1 and NaDC3.

Cat. No.	Product name	Field of application
DC11966	PF-06678419	PF-06678419 (PF06678419) is a potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.44 uM.
DC11967	PF-06649298	A potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.