Thalidomide-5-CH2-NH2 hydrochloride|CAS 1010100-22-7|DC Chemicals

Cas No.:	1010100-22-7
Chemical Name:	5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
Synonyms:	5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride;W15813;HY-W129872;Thalidomide-5-CH2-NH2 (hydrochloride);DA-68111;5-aminomethyl-2-(2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione hydrochloride;SCHEMBL1403707;Z3153424569;5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;1010100-22-7;EN300-27183929;AKOS040756415;ODZXEQVQLJKSQH-UHFFFAOYSA-N;Thalidomide-5-CH2-NH2 hydrochloride;CS-0187989;MFCD32666042
SMILES:	O=C1C(CCC(N1)=O)N1C(C2C=CC(CN)=CC=2C1=O)=O
Formula:	C₁₄H₁₃N₃O₄
M.Wt:	287.270723104477
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC39709	Lenalidomide-Br	Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs.
DC72888	Z0933M	Z0933M is a potent S phase kinase-associated protein 1 (Skp1) inhibitor with Kd of 54 nM, potently inhibits Skp1-F-box protein-protein interactions with Ki value of 231 nM in FP-based in vitro competition assays.
DC47206	Thalidomide-5-CH2-NH2 hydrochloride	Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
DC42464	CRBN modulator-1	CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM.
DC11579	VH032	VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM..
DC11565	E3 Ligase Ligand 2	E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology.
DC11578	VHL Ligand 3	A VHL ligand for PROTAC..